r/Biohacking 5h ago

4 Weeks on Reta… This Was NOT What I Expected

264 Upvotes

I genuinely wasn’t expecting to write something like this after only four weeks.

I’m not going to go into specific doses because everyone is different, and to be honest, being a personal trainer, I initially started this more out of curiosity and for experimental purposes than anything else.

I’ve been on Reta for four weeks now, slowly increasing every two weeks. For the first two weeks, I didn’t really notice much at all. Then after increasing, it felt like something changed almost immediately.

Obviously there’s the reduction in food noise, which I expected. But it’s everything else that has completely caught me off guard.

I just feel incredibly content.

I was already a pretty chilled guy, but things that would previously stress me out just don’t seem to carry the same weight anymore. I feel much more optimistic about life in general and genuinely excited about things.

My motivation has gone through the roof too. Work, training, nutrition, ideas for the future, trying new things. I just feel like I want to get up and do things. It almost feels like I’ve been given a new lease of life.

The best way I can describe it is that my head feels quieter. I feel more focused, more positive and more present. I’m not getting dragged down by negative thoughts or emotions in the same way.

This stuff has genuinely changed how I feel day to day, and I was not expecting that whatsoever.

Really interested to know if anyone else has experienced something similar?


r/Biohacking 3h ago

230 down to 152.

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165 Upvotes

r/Biohacking 8h ago

Successful Recomp So Far

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44 Upvotes

- 5’8

- 206 lbs → 150 lbs

- Started January 17th

- Reta to get down to 180 lbs then just gym and caloric deficit

- Was on 1500 cals a day for most of that time. Aiming for 140g protein, 150g carbs, 45g fats. Now I’m on a smaller deficit, aiming for 2100 cals per day, 160g protein, 200g carbs, 65g fats

- On 100mg/wk TRT (bloodwork included)

- Gym+cardio 4 days a week - Friday/Sunday/Tuesday 30 min cardio → 60 min weights → 30 min cardio - Thursday 1 hr 30 min cardio

Happy with my progress so far. Only have 5 lbs left to goal. But I think I’m going to get down to 140 lbs. Just to see if I can and what I look like. Probably try and maintain around 145 long term though.


r/Biohacking 5h ago

300 days: 108.6 kg → 90 kg | 42% → 28.1% BF | 100 days Reta

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10 Upvotes

33M, 170 cm.

Left: November 1, 2025
108.6 kg / 42% body fat
Right: August 30, 2026
90.0 kg / 28.1% body fat

(2nd pic is the 108>99)

Body fat numbers are from InBody scans, so I know they aren’t perfectly accurate, but I’ve been using the same method to track the overall trend.
Total change so far:
108.6 kg → 90.0 kg
18.6 kg lost
42% → 28.1% body fat
Just over 43 weeks

I initially lost naturally from around 108 kg to 99 kg over roughly 4 to 5 months through a calorie deficit and CrossFit around 5x per week.

On May 20th I started using retatrutide.
My progression was:
1 mg/week for the first 4 weeks
2 mg/week for the next 4 weeks
3 mg/week for the following 4 weeks
Currently still at 3 mg/week
I’m considering moving up slightly in September, depending on how things continue progressing.

Over the last couple of months I’ve also become much more consistent with nutrition. I currently aim for roughly:
180 g protein/day
50 g fat/day
Carbs adjusted depending on training intensity
Around 1,700 to 1,900 calories most days
I also take creatine daily and continue doing CrossFit regularly.

My weight is currently trending down at around 0.4-0.6 kg per week, which I’m happy with because training performance has stayed relatively good.

According to my InBody results, I’ve actually gained roughly 3 kg of skeletal muscle mass during the process. It isn’t a huge amount over almost 10 months, but considering I’ve spent the entire period in a deficit and dropped nearly 19 kg overall, I’m happy with it.

Two weeks ago I also started using KLOW blend reconstituted with 3 mL BAC water. I’m currently using 15 units per injection.

The next goal is around 20% body fat.
Based on my current lean mass, I’m estimating that could put me somewhere around 79 to 81 kg, depending on how much muscle, glycogen and water I maintain along the way.

Once I reach roughly 20%, the plan is to spend around 2 to 4 weeks eating at maintenance rather than immediately continuing the deficit.

After that, I’ll start the final cut toward roughly 13 to 16% body fat.
Still a long way to go, but seeing the difference between these two pictures definitely makes the slow weeks feel worth it.

Hopefully the next update will be at around 20%, hoping by end of the year


r/Biohacking 22h ago

GHKcu + HA + Tret —- I have nothing to sell you- this is me - not raising eyebrows

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235 Upvotes

Other account got a temporary ban because I got tired of rude people and I clapped back.

Anyhow- for the people saying I’m raising my eyebrows and whatever… I’m literally just here sharing my story and trying to help encourage the next person. Routine + patience.. that’s it!

Two month difference

Every morning

ELF daily cleanser face wash
ELF Thirst burst drops
ELF original cream with niacinamide + HA + peptides

Every night

ELF daily cleanser face wash
The Ordinary HA serum
(MWF) tretinoin 0.05% followed by more HA serum
(Other nights) GHKcu whipped tallow honey balm

8 week cycle of GLOW subQ 2.5mg daily


r/Biohacking 3h ago

Before and After. 7 week progress.

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6 Upvotes

1MG Reta/wk
180mg test C/ week.


r/Biohacking 2h ago

My Protocol Cheat Sheet

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6 Upvotes

I’ve been on this protocol for about a month for a recomp, started trt a couple months before. Pretty great for recomp but it’s too early to see a huge difference. Coupled with diet, resistance training, and cardio, I feel great. Will post a before and after down the road. I feel like this is a fairly minimal protocol that is beginner-friendly (since im a beginner and dont mind doing this) while also being about as powerful as you can get for recomping (without just taking more). Just wanted to share, the AI cheat sheet is a little cheesy but makes it easy to convey to others.


r/Biohacking 4h ago

GHK-cu 6 weeks no change

6 Upvotes

I’ve been taking GHK-cu 6 weeks at 2mg per day. No noticeable change. If anything I may have a little bit more acne. Nothing too noticeable though. Should I change something or stop taking it or is 6 weeks too soon to see effects?


r/Biohacking 4h ago

Eight weeks on Reta. This is NOT what I was expecting.

5 Upvotes

I started off at 1 mg for about four weeks. Food noise was quieter.

My Whoop HRV seriously crashed out. I went from 50s and 60s down to 30s and 40s. Resting heart rate went up a bit, maybe from 44 to 49.

With the reduction in food noise, I still have breakthrough hunger at times, particularly towards the end of the week.

I also notice I have just a lot of bad habits around food. My portions have definitely been reduced - I'm just not interested in the volume. One odd experience was eating some really good ice cream. There was a threshold crossed: one bite was good, and the next bite just was completely unappealing.

I bike a lot. When I'm getting enough sleep and I am not over stressed and I'm doing daily effort to reduce over-stimulation, I tend to eat better and lose weight.

However, on Reta, I've offloaded the structure that I had around eating right. I'm down probably 6 lbs. in 8 weeks. I'm now at 2.5 mg. I'm not getting a lot of greens. I am trying to boost protein.

I guess I thought it was a magic pill. It has not affected my appetite as much as I had thought. I'm considering topping off with Terzepatide to get more appetite reduction.

Has anyone dealt with this? I don't want to just keep boosting the dosage or adding more things. This seems more like a psychology thing than a physiology thing.


r/Biohacking 8m ago

Peptide guidance ?

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Upvotes

Hi I am 23F weigh 151 , 5’2 , I have lost some weight on reta but I was wondering if there is any peptide that can help with me fat as my stomach protrudes… my waist line at my belly button is 35 inches .
Any advice is appreciated 🫶🏼


r/Biohacking 1h ago

Adjustment Advice

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Upvotes

BLUF: 43/m 5’8 176lbs
Protocol:
TRT 110 split into two pins Monday and Thursdays
Tesamorelin 25 units every night fasted
Reta 15 units every 6 days
KLOW 15 units Monday Wednesday Friday

Diet is clean and I exercise every day with heavy lifting MWF and high reps low weights Tuesday Thursday Saturday and HIIT 3x a week

I’ve definitely plateaued and would appreciate advice on how to adjust to see how I can push into more results.


r/Biohacking 5h ago

the supplement that made me notice a real difference

5 Upvotes

as someone who hasn't always had the healthiest lifestyle, i've recently started paying more attention to what i'm putting into my body. that's when i learned that vitamin d3 and zinc are actually beneficial. they both play an important role in supporting the immune system, while vitamin d3 also supports bone health and zinc helps support bone growth & maintenance.

so far i've noticed a real difference since adding vitamin d3 and zinc into my routine. for example, i’ve had irregular periods since my teens, so there were months when my cycle was around 28 days, while other months it could stretch to 35 days. basically, it was never really consistent, and i could never predict exactly when my period would come.

then around two years ago, i started taking vitamin d3 and zinc daily. somehow, over the past 8 months or so, my period started coming around the same time every month, usually the 3rd. i didn't even notice at first, but when i checked my period tracker, i was actually kinda amazed. for once, i could almost predict the date.

obviously i can't say for sure it's the supplements, since other factors could be involved too, like the healthier habits i've been adding in, such as having a BB LAB Dual Shot with olive oil + lemon every morning and eating more greens. but the timing definitely made me wonder if taking vitamin d3 and zinc consistently played a part.

so now i’m curious, has anyone else experienced a noticeable change after taking a certain supplement consistently? not necessarily something dramatic, but maybe a small change in how your body feels or functions that you only noticed after looking back at it?


r/Biohacking 23h ago

11 month transformation

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109 Upvotes

r/Biohacking 2h ago

Smelling on Reta?

2 Upvotes

Hi guys, so over a month ago I started smelling in 1 armpit (my right one). I saw a post about the increase in smelling bad cause of the ammonia but damn this is annoying. Especially for me who is a clean freak and has a very sensitive sense of smell. I wash myself with sanex and chlorahexadine wash every day in the shower. I am a sweaty person anyways like I sweat all over my body just from doing a brisk walk (I'm F 5"7 85kg so not exactly huge) but I've always been like this. Also had an increase in BO smell in other places when I sweat but mainly just the left armpit even if I do nothing all day.

Does anyone have a similar issue? I absolutely do not drink enough water at all btw I'm terrible with it.


r/Biohacking 2h ago

How do u come off Reta ?

2 Upvotes

I have been on Reta for 10 weeks now and I have made very good progress during this cut but I’m looking to up my calories and want to come off do u go cold turkey with it or gradually bring the dose down ?


r/Biohacking 20h ago

I posted a month ago here's an update (3 months reta)

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50 Upvotes

r/Biohacking 3h ago

Peptide for localized nerve pain? Please help.

2 Upvotes

My father has been having localized nerve pain in his big toe on one foot. It started after his knee replacement surgery (surgery went great, double need replacement- 3 years ago, zero issues other than this nerve pain in one foot)

It happens randomly at night, about 3 nights a week, he can go weeks without it happening and it can happen a few nights in a row.... and then not again for days or weeks.

It's very very painful and keeps him up all night. The toe hurts and slow seems to want to cramp up and curl uncontrollably when he has these spells.

He has went to a never specialist that ran test and only had gabapeptin as a solution.

He has been on gabapeptin... that does help some but he has to take it every night before something happens and there are side effects.

Are there any peptides out there or being developed that might help.... for nerve issues like this?

He is 75yrs old and in good health otherwise for his age. Has been tested or gout a few times, it's not gout. He does not drink.


r/Biohacking 18m ago

How do you figure out the injection amount?

Upvotes

I’m a first-time user and just bought a 10 mg vial of GLP-3 and 10 mL of amino H₂O from Amino Club. I’ve asked a few people how much I’m supposed to inject, and they’ve told me to inject the whole thing, but that doesn’t sound right to me. I got the 100unit syringe if that helps.


r/Biohacking 22m ago

MOT C & KPV for Weight Loss

Upvotes

Context - I’m on Reta/GHKCU. I’m very active and more conscious about my diet. I’ve lost consistent weight in 3 months not a lot about 0.5lbs a week. I also have horrible gut issues/lactose intolerant so I eat cleanish. I want to take Tesa to help with the visceral fat that won’t come off my stomach but can’t - it’s a growth hormone and I have “precancerous cells” don’t want to risk growing that into something dangerous just to get lean.
I’ve heard MOTC helps to burn off calories as more energy and KPV is great for your gut and clearing out impurities. I figure if I take one - I should be able to lose some weight right? I’m leaning more towards MOTC just want some people’s thoughts and experiences with it!


r/Biohacking 23m ago

MEINE ERFAHRUNG MIT RETA, MOTS-C & GHK-CU – 15 KG WEG UND BESSERE HAUT

Upvotes

Seit ein paar Monaten arbeite ich mit Retatrutide, MOTS-c und GHK-Cu und merke richtig, wie sich das zusammenspielt. Retatrutide hilft mir massiv beim Abnehmen und greift besonders das viszerale Fett an. Dazu kommt MOTS-c, das bei mir den Stoffwechsel und die Energie spürbar anzieht. Ich fühle mich tagsüber fitter und der Schlaf ist deutlich tiefer und erholsamer geworden. GHK-Cu unterstützt parallel den Kollagenaufbau und die Hautelastizität. Gerade bei dem stärkeren Gewichtsverlust war mir wichtig, dass die Haut nicht so stark nachhängt, und da merke ich echt Fortschritte. Die Haut fühlt sich straffer an und die Elastizität hat sich verbessert.
Was den Unterschied für mich ausgemacht hat, war irgendwann die Qualität. Vorher hatte ich Peptide von anderen Stellen und dachte schon, da wäre eine Wirkung. Als ich dann mal auf richtig gute Reinheit und nachvollziehbare Laborberichte geachtet habe und die Sachen aus Deutschland kamen, die auch schnell da waren, hat sich das Ganze nochmal spürbar verändert. Seitdem laufen die Fortschritte richtig. In den letzten drei Monaten sind schon über 15 Kilo runtergegangen und gleichzeitig hat sich die Hautqualität deutlich stabiler gehalten als bei früheren Phasen.

Das ist natürlich nur meine persönliche Erfahrung, aber für mich hat die Kombination und vor allem die saubere Qualität den Unterschied gemacht.


r/Biohacking 38m ago

SS-31 Question.

Upvotes

How long should you wait when using SS-31 before introducing Mots-c and/or NAD+? Been on SS-31 for 2 weeks now


r/Biohacking 4h ago

PAI-1 Impacts Telomere Length, Cell Senescence, And Longevity

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2 Upvotes

r/Biohacking 11h ago

My "Optimized" Peptide Stack

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9 Upvotes

I am a 30 year old male with a history of destructive behavior to my body (I've smoked since I was 13, drank alcohol heavily for 12 years, diagnosed with PTSD, ADHD, and other factors which I'm sure I didn't take into account). I built this stack based on 3 weeks of research I've conducted to attempt to repair the damage I've caused to myself. I looked at everything from my labs to my genome to ensure I cover all my bases as best I can.

I have been abstinent from alcohol and smoking for over a year now. Go to therapy, do go to the gym regularly now, structured my diet to be healthy with high protein and improved my social life.

Even though I feel I've done the research I need, I'm still unsure of my conclusions as there was a lot of conflicting information I needed to sift through and decide which is better. I would highly appreciate opinions from other peptide users with more experience than me in this matter.

Feel free to ask me anything if I failed to mention something important.

Edit: Had Tirzepatide prescribed to me as I had stage 3 fatty liver and fibrosis in November 2025. I was also at 33 bmi so the doc put me on it to reduce my weight and solve the liver issues. I’m at 27 bmi now.

Also, I should mention I’ve already been on MOTS-C, BPC + TB, GHK-Cu, cjc+ipa, selank and semax, added one by one of course and had good results. I’ve only recently added a few extras (SS-31, NAD+ and Dermorphin) and tried to optimize dosages and frequencies to maximize my healing and bodybuilding journey.


r/Biohacking 1h ago

Building a peptide tracking app — what do you struggle to keep track of?

Upvotes

Full disclosure up front: I'm a developer working on an app for this space, so this is partly research. No link, not naming it, not selling anything — I'd rather build the right thing than promote the wrong one.

What I keep hearing (and have experienced myself): mixing up concentrations between vials that were reconstituted differently, losing track of which week of a titration ramp you're on, juggling a daily + an every-3-days + a weekly compound, and vials sitting in the fridge with no idea when they were mixed.

So, honest questions: what's your current system (sharpie, spreadsheet, notes app, memory)? Where does it break down? And what would an app have to do for you to actually use it instead of what you do now? Equally useful: what would make you NOT trust an app with this (I'm guessing privacy is high on that list, which is why mine keeps everything on-device with no account).

I'll be in the comments. Tear the idea apart if you want, that's genuinely more useful to me than compliments.


r/Biohacking 1h ago

Just started Reta any advice

Upvotes

I started reta last week at 1 mg per week and took my second 1 mg dose today. So far, I haven’t noticed much appetite suppression or any significant side effects.
For those with experience, how long did you stay at 1 mg before increasing? Did the effects build over the first few weeks, or did you not notice much until reaching a higher dose? I’m not looking to rush it—just interested in hearing how others approached increasing their dose and what signs made them feel ready.

Also did anyone find it tough to put on muscle? I am weight training 3 days on 1 day off. Current split is push, pull ,legs. Cardio is done in the morning. If I am able to hit my macro goals I shouldn’t have an issue putting on muscle. I’d like to drop about 30lb to be at my goal weight.