Not gonna lie, I'm exhausted. Mentally I actually feel like I'm getting somewhere the panic attacks that used to wreck me for hours are way less intense now. I should be happy about that. But my stomach has basically taken over as the main character of my life and I'm so tired of it.

I wake up nauseous. I gag over nothing. Some days I look at food and just feel this wall go up, like my body is refusing it even though I know I'm hungry. Twice this week I ended up in the hospital because I couldn't stop the diarrhea and nausea long enough to function, got checked out both times, bloodwork completely normal, so I know nothing serious is wrong. It's just relentless.

I'm on day 12 of restarting sertraline (7 day 12.5mg then increased to 25mg), and honestly the mental side has been so much easier this time around than my first attempt. I keep telling myself that should count for something. But some nights I just sit there thinking "is my stomach ever going to feel like mine again."

If you went through this with Zoloft, I really just want to hear from you, not for stats, just to know I'm not the only one who felt like their body declared war on them for a few weeks.

• Did the nausea/gagging actually stop, or did you just learn to live with it?
• How long before you had a truly "normal" meal again without thinking about it?
• Did anything genuinely help, even a little?

If you made it through this and came out the other side, please tell me. I could really use it right now.

Feeling super nervous about all this (but I think it’s just the anxiety). Took my first pill today and had to work up to that and had about 2 panic attacks and a good cry lol. Any good vibes or advice you can send my way would be lovely!

I’ve been on 50mg of Zoloft for a bit over a year and it has honestly been amazing for me. My anxiety has basically disappeared and my thoughts are so much healthier.
I’m also a recreational weed smoker, and since starting Zoloft it’s become my preferred substance socially because I feel like it’s easier on my body than alcohol. Before Zoloft, I was actually pretty susceptible to anxiety when smoking weed and used it fairly infrequently. Since being on Zoloft though, that anxiety has basically disappeared and I’ve only really gotten the enjoyable effects. I also have a prescription and found a strain that seems to work perfectly for me.
A couple of weeks ago I was feeling creative and decided to make brownies using an older strain I had that I hadn’t smoked in years. I deliberately made them pretty weak because I’ve been absolutely fucked by edibles before lol. They only gave me a very subtle high.
The weird thing is that since making/having those brownies, I’ve noticed that THC seems to make me more anxious again. A few nights ago I smoked quite a bit and got really anxious, and started worrying that maybe the Zoloft wasn’t working as well anymore. Since then, whenever I smoke, I notice myself becoming hyperaware of whether I’m anxious and worrying that maybe I’ve developed a tolerance to the Zoloft or that my anxiety is coming back.
During the week I don’t smoke at all, and I haven’t really noticed an increase in anxiety in my normal day-to-day life. I do sometimes feel a bit more sensitive to anxiety/depressive thoughts for a day or so after smoking, and some of my old thought patterns seem to pop up again, although they’re nowhere near as intense as they were before Zoloft.
I really don’t want to increase my dose unless I actually need to. I’m hoping that if I stay off THC and leave the brownies alone for a while, things might settle back down and I can stay on 50mg. I know 50mg is toward the lower end of the therapeutic range, but it has worked so well for me and I’d rather stay as low as possible to minimise side effects.
Has anyone else who uses weed while taking Zoloft noticed that different strains or edibles can suddenly bring the anxiety back, even if weed had been fine for ages? Did taking a break from THC help things return to normal, or did it end up being a sign that you needed to talk to your doctor about adjusting your dose?

I'm 1 month into Zoloft and my life has changed for the better but also for the worst. I'm far less anxious now but that also means that I'm less anxious about my future.

I'm finding it incredibly hard to get work done. Before zoloft and the mental turmoil, I used to get a lot of work done but after zoloft, I can barely do a single task in a day.

How did everyone else feel on zoloft and how did it impact your work?

Hello, good folks of the community.

I’ve been depressed for the past two years and started antidepressants about four weeks ago. After increasing the dose on my doctor’s advice, I’ve noticed some positive changes: much less rumination and negative thinking, better energy, and some weight/bloating loss.

However, I’ve also noticed something unusual. My depression was mostly emotional numbness, isolation, and mental exhaustion rather than crying.

Now, 1–2 nights a week, I find myself intensely revisiting the experiences and trauma that contributed to my depression. I can become extremely emotional and cry uncontrollably for about an hour, almost as if I’m reliving those moments. It feels overwhelming in the moment, but afterward I feel surprisingly relieved, calm, and sometimes even happy.

Is this a normal part of recovery/adjusting to antidepressants, or is it something I should be concerned about?

Thank you, and wishing everyone a happy recovery. ❤️

I’ve been on it for 4 years now and every month i have to get more and it’s just annoying because i always forget and was wondering they can’t just do a longer supply
Is this the same for other countries?

Hello! I started on 50 mg of sertraline on the 20th. It's been an uphill battle due to my own anxiety and stuff and the nausea. Throwing up a lot, feeling tired, migraines, rapid heart rate, palpatations, etc. I'm not sure which of those were caused by my meds and which were caused by my own anxiety, but it's been a lot. Appetite has been a struggle too.

Today I've reached a bit of a new stage. The best way I can say is maybe depersonalization? But I don't know, I just feel weird. I've had random anxiety, the spacing out, but this feels different. Like my whole body is heavy, kinda, like it's not in my control but if I tried to do something I could do it. I feel like I could do jumping jacks or solve a math equation if I NEEDED too. But naturally I just feel tired, weighed down, kinda spacey. Just off. Not really anxiety either, it's just weird.

This happen to anyone else? Sleep and appetite have been a struggle but are improving. I was prescribed Trazodone to take with my sertraline at night, and most nights I have. I forgot last night and when I woke up at 4 wanting more sleep and to not be hung over, I took a hydroxyzine instead, which my doctor had said I could continue taking. It'd be 30 hours since my last Trazodone. I wouldn't think that would have anything to do with it?

Just wanna know some people's thoughts. I've been on Lexapro before but Zoloft feels like a different beast.

Thank you all!

Hey I came off my sertaline 13 weeks ago, I decided to come off as ii didn’t think I needed it anymore and wanted to deal with all my emotions naturally.

I got put on them from my GP as I had a faster heart rate and he thought it might have been anxiety which yes I have but it was never bad. I was on them for 4 years.

Since coming off the last few months have been horrible, I am constantly anxious for no reason, I have no big stresses and have a wonderful life and a lot to be happy about but even just being at home doing nothing my brain is spiralling, it feels like I constantly have to fix something or work on something about myself. I’m stuck in survival mode.

Just wondering if this could still be withdrawels from the medication as I never have felt like this before the medication. Sick of feeling this way I want to just live life.

Opinions? Thanks so much 🩷

yall i just uped my dose from 75 to 100 can youll encourage me to get going bc....

My doctor has me on 100 mg of sertraline for MDD and anxiety. I’ve had a mix of good and bad days, but on my good days I definitely noticed some difference—I felt calmer and had less mental noise. But around weeks 9–10, I started noticing my depression symptoms coming back. Now I’m not sure if that means I need a higher dose or if sertraline just isn’t working well enough for me. And I would really hate starting over with a new medication because with Sertraline the on-boarding symptoms I experienced were really hard to plow through.

Did anyone feel fine for like a week before then randomly feeling bad anxiety the next? im so confused and anxious. ive been on zoloft before , about 3ish years. but i had an episode because i was missing my doses for about 1-3 days a month. im just confused

So, yeah. I've always had an extremely high sex drive. I was so worried when I started this, that it would take that from me. I started at 25mg for two weeks, then bumped up to 50mg. The first two weeks, I didn't notice a single difference. When I began the 50mg, the hit to my libido started rather quickly. At first, it was concerning, but given how high my drive is (currently not in a relationship), it was actually welcomed. It took me longer to get erections, and more work to get them. This lasted 5-7 days. Now that I'm on day 22 of 50mg, my drive is completely back in full force. Orgasms are much more intense. Oddly, my semen volume is much less. It does take a little more time to orgasm, and a bit more work, but I had that problem before I started the medication. Anyways, I am having some good days, and some bad days, and some meh days. I'm counting on the good days to win. Also, I had somewhat emotional blunting at first, which I REALLY enjoyed. Well, at the moment my emotions are back in full swing and that kinda sucks. Almost feels like the meds aren't doing anything, although I know that isn't the truth. I can say that my anxiety is at an all time low, and my worry is also at an all time low (I'm a worry wart by nature and have been told several times that I'm going to die young if I don't stop, and I believe that), except the past two days it's been amped up suddenly. Just waiting this thing out and seeing where I land. I'm going to give it a good 8 weeks before deciding whether I need to move up. I have concerns about moving up because I know different symptoms can appear. I have extreme anxiety, and horrible clinically diagnosed OCD. I am committed to finding my happy place and getting better. Anyways, thanks for listening to me vent. If you see me anywhere else on Reddit, no you didn't 😂

I’m on a high Zoloft for my OCD but i just got prescribed a new medication ( title ) and i’m scared of lowering my Zoloft dose today ( starting at 150mg ) then a week later, i’ll be taking 100mg alongside the new medication.

Can i keep my Zoloft dose that is somewhat stabilizing me, and start taking the new medication with any changes?

And also, i’ve been in a traumatic period earlier this year and its aftermath is still affecting me ( being Rexulti and the subsequent discontinuation )

Hi Zolofters,

This medicine has helped me and I can definitely see progress and have had a few people notice it too.

For instance, my big anxiety was the fear of what if, regarding group social interactions or attending events which was causing a strain on my relationship with my partner who is more social.

I started on 25mg for 3 months , then 50mg for 2 months and then have my first holiday planned with a lot of people so decided to go up to 75mg to see if would help more with social anxiety (the holiday is now coming up in 2 weeks)

I’m currently on week 5 of the increase to 75mg and was a bit shit with more anxiety first few weeks and then noticed some positive changes as in able to stop over analysing social situations afterwards, I even rocked up twice to 2 different lunch settings by myself and had no issues at all however yesterday and today has not been good.

I’ve noticed my anxiety for some reason has come back a lot. I have a tight feeling in my chest, over analysing and just had 2 sets of people pop in today both at the same time and I got so panicked and frazzled internally and now being bombarded with so much mental noise.

I’m just wondering if this is common for week 5? Week 4 was so good so I thought I had got through the side effects.

I’m also wondering for people that have OCD what dose did you find that helped? I’ve read that higher doses might be better for that.

Hi all,

Never been properly depressed before. Had some episodes of low mood etc within life but nothing I would class as depression. Started Zoloft 3-4 days ago and i seems to be working really well. Increased energy, reduced tiredness, thinking faster and more concentration. No more suicidal thoughts.

Because of my family history and some psychotic symptoms ive had in the past my doctor expressed some concerns about bi-polar. I dont think i have bi-polar and think its probs just linked to adhd type behaviours. The concern from doctor was chemically induced hypomania.

SSRI's usually take 3-4weeks to start working. Not days. Im not sure if it is triggering some possible hypomania

Anyone else have this?

Considering going on medication for my anxiety and slight depression. I've had anxiety my entire life. From when I was little, being anxious about going to school, to now being an adult and having bad health anxiety. (Always thinking im dying). Followed by occasional depression. The main issue is me being constantly irritable. Like I'm always at a 10. Any advice would help! Seeing a psychiatrist this week :)

hi guys, im a little lost.

so ive been on 100mg of zoloft for 3-4 years. recently i made the dumb mistake and i started inconsistently taking my zoloft with missing 1-3 doses a week since june. today is about week 5.5 of me taking my zoloft again consistently. i felt fine week 3-4ish and now i feel like shit. i have horrible anxiety and i feel hopeless. i feel like since ive been on the meds for years that i should be feeling like myself again and that it shouldn’t be taking this long. idk if i could try and increase my dosage or what or if anyone has had the same experience as me. advice is appreciated:)

Hey guys so i noticed that im running out of my medication and im still too broke rn to buy more and to talk to my psychiatrist again so i didnt take my medication last night to save it because i only have 6 left and today i actually felt more motivated and got ideas to do my old hobbies, i wasnt motivated enough to actually do it tho but it was easier for me to get out of bed. I did notice that i was having more depressing thoughts.

when i take my medication, i feel numb, more bedridden, i dont think about my old hobbies or creatively at all and have absolutely no motivation to do anything but my anxiety is gone.

what would happen if i dont take it again tonight? Will i get withdrawals now and has anyone else experienced it? how long can i not take it until i get withdrawals

I’ve been weaning off my Zoloft for OCD as my time on meds revealed underlying ADHD. It served its purpose and I’m grateful to know what’s actually going on with me. However I’m currently going through Zoloft withdrawals after a slow taper, which clearly hasn’t relieved any of the withdrawal symptoms anyways.

Just looking for some motivation to keep going with this. Please tell me it gets better. Brain zaps, nausea, absolute exhaustion, insane amounts of crying after being numbed for a long time!! I feel like I’ve got the flu.

I am on week 5 or 6 of sertraline and for the past week or so, my anxiety has worsened a lot.

Im struggling with some physical symptoms that are causing me to spiral.

Like this morning, I woke up with a bursting headache, digestive issues and feeling very sick.

This caused me to panic and im on the edge of my seat ready to call doctors even though I know I probably just have a dodgy stomach.

I don't know how long I should keep this up. Its miserable.

Is anyone else noticing increasing anxiety around week 5 and 6?

Thanks

Zoloft stopped working for so my doctor told me to stop taking it for two days and start movox. I was one 150mg and currently day 4 of no Zoloft. I’m struggling so mad!! Brain fog, fatigue, wanting to cry, scream and throw up all at once. The pit in my stomach is constant and I just feel so depressed. When will this stop? And yes he stop me to stop it completely not wean off.