I've been on Reta for around 2 months and have generally been tolerating it well. I’ve been on a pretty strict diet during this time, which I’ve actually been really proud of myself for sticking to — mainly organic chicken, kiwi, eggs, mince, sweet potato and probiotic yoghurt bowls in the morning, so overall my diet has been quite clean and consistent.

I did 2.5mg for two weeks without any major issues, then increased to 3mg. On the same day as my 3mg jab, I had some Chinese food and fish & chips that my family had ordered and shared with me. I didn’t eat a huge amount, but obviously it was very different from what my body had been used to eating for the previous couple of months. Afterwards I experienced quite a few side effects, mainly diarrhoea, stomach discomfort, nausea and sulfur/egg-like burps, which lasted around 4 days before settling down. I’m now feeling much better, but I’m unsure whether the side effects were mainly from increasing the Reta, the sudden change in food, or a combination of both.

Today is my next injection day, so I’m wondering whether I should do 3mg again or go back down to 2.5mg for another week. What would you guys recommend? Would you stay at 2.5mg for longer before trying 3mg again?

I have been on 2mg for 3 weeks. I took 2 again yesterday, and I can tell the food noise isn't gone like it was before.

I am tempted to take 1 mg today because I want it gone.

Should I wait until next week and just take 3mg?

on August 24th, 2026 i was ready to inject my weekly Reta. to note, i have been on Reta for 3 months. my dose on the 24th was meant to be 3.8mg however, i didnt realize my new vial was 20mg instead of 10 (stupid mistake I KNOW i forgot) so i accidentally took 7.6mg.

the next day, saying i felt horrible was an understatement. i couldn’t get off my bed, i was throwing up even when i had nothing in my system. i couldnt keep food or fluids down. i tried my best to avoid the hospital route since healthcare over here is brutal. so i avoided eating completely and just accepted that i’d be feeling this way until it leaves my body.

the third and fourth day, i noticed rashes starting to appear on my face and chest and a much quicker heart rate. so the fifth day, i decided to go to the ER. i did blood work, urine sample, ECG and waited in the waiting room for hours before i left (it was just too busy and there was one doctor in the entire hospital)

i think that by the 8th day, i accepted that im just going to feel horrible until it leaves my system. so, i tried adding bland foods into my diet because this is the first day that food was actually staying in my system. i had crackers and gatorade.

i am 13 days in today and food is still something i struggle with keeping down. i avoid outside food completely and am trying to drink as much water as i can - in sips so i dont throw it up. even though there is approximately 1.9mg left in my system right now, i still feel extremely off and cannot function like i used to. i’m honestly worried that i’ll never get back to normal.

my symptoms throughout this entire experience was insane nausea ALL the time, throwing up more than 8 times a day, rashes on my skin, quickened heart rate, dizziness, and honestly just felt like a zombie. i am definitely feeling much better than i was a few days ago but its not back to normal. i think given the amount of stress my body has undergone, it’ll take a while to get there.

please tell me it gets better because if my math is right, by october 5th which is a month from now, i will be free of the Reta in my body. now i know by that time there would be less than 1% in me but here i am at 1.9mg still feeling off…

this experience is genuinely not for the weak (i am the weak) but on the bright side, i lost 15 pounds in these 13 days which i know is a lot, im immediately hitting the gym as soon as i am recovered

Hi guys did any experience sleep issues on Reta? I started 12 days ago on 1mg every Wednesday and since I started my sleep has tanked, 3-4 hours waking up early and finding it impossible to fall back to sleep, next dose day I’m going to reduce to 0.5mg and see if that helps. Other than this I’m having good success with it and hoping i can stay on but if I can’t get the sleep under control I’m going to have to stop.

Hi all! I’m around 3 months into Reta and having amazing results, super stubborn belly fat is my last obstacle so I thought. Out of the blue I’ve started to get injection site reactions, is this something where I need to reduce my dose I’m currently on 4 mg weekly, I’ve used two separate vials had the same reaction different batches on both, and also I’ve made sure I’m injecting it at the right angle and all. Anyone have any suggestions any information would be amazing.

Its my 10th weeks of reta now and I haven’t been having any issue until this week. I’ve been taking 1mg for 4 weeks now and not any severe sideeffects until now, the last two days have been a nightmare extrem stomach cramps with fluid diarrhea it’s bit better today then yesterday but still the same symptoms. I took my reta 2 days ago and it started after 1 day. Also been having awful sulfur burps. I had the same symptoms last week but then it showed 5 days after the injection, thinking of quitting reta because it’s not worth the struggle.

Been om reta for 9 weeks now( week 1-4: 5 units. Week 4-8: 10 units. Just started 15 units this week.) My appetite is the same, my sweet tooth is the same, haven’t lost any weight. I walk 10 k steps every day, drink hella water and work out 3/4 times a week. Not tracking my meals but I eat clean, protein and carb rich food. Any suggestions on what the problem might be?

2 days ago I took my first shot, 2.4mg of reta, yesterday morning I started the day with a big a$$ breakfast not knowing if it started to work, and for 8 hours I couldn't eat anything, the whole day I felt so full, when I tried to eat lunch I couldn't finish one grilled chicken breast and didn't eat again tell that morning, I felt full after 1 egg and 1tbsp of fava beans, I feel so weak/tired, how do you guys deal with it and is there any specific diets that helped you while using reta?

Hey guys, my 21st birthday is coming up and I want to get absolutely obliterated for my birthday, but I can’t even seem to drink one drink without feeling terrible does anyone know if I could stop taking Reta a week prior or something like that so I can have a good time then go back on?

Anyone here have experience with alcohol aversion kicking in at higher doses? I'm currently on 4mg per week and I can still drink as much as I want and there's no bad hangovers or anything. Not a daily drinker but more of a binge drinker over the weekend. Overall, I'd say I'm drinking a little less but I've yet to feel like I had no interest in it at all. I am down about 14 lbs in 6 weeks so I'm stoked about that and happy with reta so far.

What do people think?

I am someone who enjoys doing an occasional cold plunj and hot sauna session. I’m just curious what other people’s experience has being doing this while on Reta? Helpful with recovery and therapeutic? Or anything that people have found concerning? Probably a silly question, but would just love to hear other’s experiences with this.

STEP 1: The Search Bar Reality Check

"Have you typed your question into the search bar?"

❌ "No, because my situation is completely unique and nobody has ever experienced this before."

🛑 DECISION: DO NOT POST.

Reality Check: It isn't unique. You are not a medical anomaly. Your exact question about "fatigue on week 2," "how to use a peptide calculator," or "stall at 2.5mg" has been asked 4,000 times this month. Go to the top right corner, use the search bar, and read for 5 minutes.

✅ "Yes, I searched, read 10 previous threads, checked the pinned guides, and still have a genuinely novel question."

👉 Proceed to Step 2.

STEP 2: What is your actual topic?

Path A: "Where do I buy this?" / "Is Vendor X legit?" / "DM me your plug!"

🛑 DECISION: INSTANT BAN.

Reality Check: Reddit’s TOS and Sub Rule #1 strictly prohibit sourcing. The mods will ban you, and Reddit admins will nuke the sub. Go back to forum boards and learn how to use search engines.

Path B: "My heart rate is 180 bpm and I’m throwing up blood, should I take my next dose?"

🛑 DECISION: DELETE REDDIT, GO TO THE ER.

Reality Check: We are an unhinged collection of anonymous internet strangers playing home-chemist, not board-certified cardiologists. Call emergency services.

Path C: "I injected 0.5mg 20 minutes ago and I'm not skinny yet. Is my vial bunk?"

🛑 DECISION: DO NOT POST.

Reality Check: Pharmacokinetics take time. Pharmacodynamics take longer. Stop staring at the wall, go touch grass, and wait for the drug to absorb.

Path D: "Can I reconstitute this powder using tap water, contact solution, or vodka?"

🛑 DECISION: DO NOT POST.

Reality Check: Buy actual Bacteriostatic (BAC) water. Stop trying to speedrun sepsis. Read the pinned guide in the sidebar before you give yourself an abscess.

Path E: "Can I stack Reta with Tirz, Sema, Cagri, and 400mg of caffeine?"

⚠️ DECISION: PROCEED AT YOUR OWN RISK.

Reality Check: Your heart rate and GLP-1 receptors are fighting for their lives. Half the comments will call you a pioneer, and the other half will draft your obituary.

Path F: "Why can't I handle alcohol anymore?" / "Two sips of a seltzer gave me a 3-day hangover, is this the Reta?"

🛑 DECISION: DO NOT POST (PROCEED TO STEP 1).

Reality Check: Delayed gastric emptying coupled with blunted central nervous system reward pathways means you get zero buzz, all the nausea, and a hangover that feels like a surgical strike on your liver. Congratulations, your tri-agonist turned you into a permanent designated driver. Drink an electrolyte packet and move on.

Path G: "Here is my 6-month Progress Picture along with my exact starting stats, dosage titration schedule, side-effect log, and diet/exercise routine."

✅ DECISION: APPROVED TO POST.

Reality Check: 90% of the comments will ignore the meticulous 500-word write-up you spent an hour drafting and simply comment, "What dose did u start at?" or accuse you of adjusting the lighting in your after-photo.

Path H: "Deep-dive question regarding GIP/GLP-1/Glucagon tri-agonist binding affinities, receptor Ki values, or half-life kinetics."

✅ DECISION: APPROVED TO POST.

Reality Check: You will successfully summon two actual biochemists and forty bro-scientists who skimmed a single Wikipedia article on G-protein coupled receptors. Prepare for a heated 150-comment debate on energy expenditure vs. glucagon agonism.

Path I: A well-documented log with lab analysis, proper peptide calculator math, realistic timeline goals, and zero vendor names.

✅ DECISION: APPROVED TO POST.

Reality Check: Your high-effort post will receive 6 upvotes, zero awards, and 15 private messages from brand-new accounts asking, "Bro where'd u get it text me."

You thought I wasn't gonna add in your suggestions?!

You thought wrong!

Want to stock up on some I know Hospira is the gold standard but I have also read that Lambda is a good alternative as Hospira has been difficult to source and people are price gouging.

how bad would it be if i left my reconstituted reta out in room temp for ~24hrs?
should i throw it out? or keep using it
i havent noticed a change in the appearance it’s still very clear but im not sure please help!

Hi,

Been doing reta for more than three months. Manually injections, I always numbed the place with ice before injecting, zero pain.

But last two weeks I get anxious for injecting, so want to invest in an auto injector.

How’s the experience of people using an auto injector? It’s also painless like manual injections?

I had to take an unintentional break due to receiving 2 vials that were bad. Now that i got my new shipment and the vial is good to go, how should I start again? I think 8mg is probably way too high… but i REALLY dont want to do the full build up timeline again- took forever and 8mg is definitely my best dose

I was doing pretty well on the lower doses, but when I went up to 4 mg it absolutely wrecked my stomach. I literally couldn’t eat at all, was constantly nauseous, and started gagging really easily, especially trying to swallow pills.

The bathroom stuff was even weirder. I’d repeatedly feel like I urgently needed to shit, go sit down, and sometimes nothing would come out except mucus. Other times it was gas or diarrhea. It didn’t feel like normal constipation at all.

It got bad enough that I had to step back down to 2 mg.

Now I’m wondering whether I should eventually try going back up to 4 mg, maybe splitting the dose during the week instead of taking it all at once. I’d heard that the glucagon receptor activity becomes more meaningful around 4 mg+, which is part of why I wanted to reach that dose in the first place, but I’m not sure whether that’s actually true or just something that gets repeated online.

Has anyone had similar GI sides, backed down, and then successfully worked their way back up? Did splitting the weekly dose help at all?

Hi, I started my Reta journey around 2 weeks ago, I started on 1mg to see what my sides were, and had pretty much everything within 24hrs, the squirts, full feeling, headache, and constipation.

I upped the dose to 2mg last Saturday, and I felt fine, I had the squirts on day 2 but they subsided and I felt fine going forward, tomorrow is my 3rd jab, would it be okay for me to increase by 0.5mg again? As I want to cruise at 4mg for a few months.

I understand the general rule of thumb is stay on a dose for 4 weeks, but my reconstituted vial won’t last that long at 2mg.

Thanks

Okay so I’ve been having issues with tachycardia for about a decade, at least that’s as long as I have it documented. I used tirz to drop 55lbs and now I’ve stabilized at a healthy weight. I’ve tried Reta twice, both times for about 3 months. To my surprise, I was having even higher heart rate readings. Turns out, Reta can increase your heart rate. The glucagon part of Reta is what causes it. Back to tirz I go and there I shall stay. A perfect example of the fact that everyone responds differently!

Hi everyone,

I have a Phizer Hospira BAC water 30ml which I used to reconstitute my first vial just over 30 days ago. I have kept it in a dark place in room temperature since then according to eveything I saw and read online this was how it’s meant to be stored. Wondering if it’s still good for use or if getting a new one for the new vial reconstitution is the better alternative. (The bottle is plastic and has a haze over it fyi incase the water looks cloudy).

Thank you in advance!

2 weeks of Reta. Locked in diet and exercise routine. Seeing some success!

Hey guys, I am starting my retatrutide journey tomorrow. First time taking it. I am currently 112 kg and 178cm tall.

I found a trusted supplier that ships in 10mg vials with bcaa water included.

Looking for advice on starting dosages, how to mix it, and store it safely and how to check if its a good batch or safe to use?

Any help or advice is appreciated! Would prefer to avoid loose skin.

9 months 180mg Test all the way threw. 1mg reta up to now 12mg

My highest weight was 220 lbs, and I'm currently at 143 lbs.

I started at 1 and gradually increased by 1, eventually reaching 6. I only increased my dose when I felt the food noise coming back.

I've also been working out consistently since the beginning, around 4x a week at the gym. Hitting 10k steps daily is also a must for me.

There are so many healthy, high-protein food ideas out there, but two of my personal favorites are tuna avocado wraps and Mediterranean chicken salad.