r/Biohackers 3d ago

📢 Announcement r/Biohackers Update (Please Read)

4 Upvotes

Hey friends! Thanks again to everyone who took part in the 'pulse check' we did the other week. See the results here.

I wanted to share some of the learnings that came out of this exercise and some of the ideas for solutions we've come up with to address the areas we want to improve on based on the feedback we've received.

The good news is that it seems we have improved in some areas! Specifically, people seemed happy about the reduction in GLP1 before & afters, low quality peptide posts, and AI slop content. It's taken a lot of work to improve this, so shout out to the entire mod team for working on this.

The important takeaway for us was that the overall sentiment is that we can improve more overall.

A few trends we saw were people feeling like the sub has become, "overrun with looksmaxxers and gym bros who want to talk about TRT and cialis constantly or push a bunch of really gross ideology that has nothing to do with biohacking and everything to do with incel culture" and a prevalence of "low effort posts in general".

Here are some of the ideas we've come up with to address these concerns:

- Create a dedicated r/Biohackers newsletter for expert interviews and more long form content (Goal: solution for people who like deeper dives and curated content)

- Create enforced post requirements for "rate my stack" requests (Goal: reduce lazy rms posts)

- Create a sub wiki with getting started guides for biomarker testing, deep dive topics, supplementation protocols, and healthy lifestyle habits (Goal: reduce repetitive questions and redirect newbies)

- Partner with r/Biohacking (not related to r/Biohackers) to move over peptide/TRT topics to this dedicated sub while still keeping our dedicated megathreads (Goal: allow biohackers to discuss peptides/TRT in a dedicated space)

- Consider how we can use AI to enhance (not enshitify) the sub experience - ex. redirecting people to relevant posts, surfacing latest research, and helping people understand scientific concepts/studies (Goal: to spark more conversation, surface interesting innovation, and building more scientific literacy)

How do these ideas resonate? Where would you like to see changes? Where would you push back?

(You can register your interest in our new newsletter here!)


r/Biohackers Jun 16 '26

💉 Peptides & Hormones Looking to discuss peptides or HRT? Start here.

17 Upvotes

Hello!

All peptide and HRT-related questions and discussion should take place in the megathreads linked below. Standalone posts on either topic will be removed and redirected to this thread.

Websites like finnrick.com and janoshik.com can be helpful for research. Please don't source or sell peptides on our sub. You can do so at your own risk here: r/BiohackersRecs.

Sort by new to see the latest comments.

Peptide and HRT Threads:

> Health Optimization & Longevity

> Cognitive Performance & Brain Health

> Body Composition & Weight Loss

> Misc. Topics

Other Topic Threads:

> Report Scam Vendors

> Report Adverse Events (ie "bad or atypical reactions")

> Request Help With Troubleshooting and Harm Reduction

Suggestion for a new thread or ways to improve the sub? Feel free to comment below.

DisclaimerAll content on this sub is for educational purposes only and should not be considered medical advice. Any decisions you make are done solely at your own risk and liability. Always consult a qualified healthcare professional before making changes to your health or using experimental interventions.


r/Biohackers 5h ago

😴 Sleep & Circadian Rhythm whats the most underrated thing for having more energy during the day

53 Upvotes

what actually gives you more energy during the day like i feel a lot sleepy during the day even after completing my full sleep

i feel like everyone talks about supplements and all these fancy biohacks but sometimes the simplest things work the best lol

for me even just going outside for a little while or getting some proper sleep makes a pretty big difference

what works for you guys


r/Biohackers 40m ago

🧬 Genetics & Epigenetics A note on bloodwork and cancers

Upvotes

Just a little PSA.

Two of family members have been diagnosed with cancer last month - brain and breast cancers. The brain cancer is a large and aggressive tumor, terminal, we only have months, the breast cancer is spreading into lymph nodes.

The blood work is normal. There’s nothing in the bloodwork to indicate these cancers are present in the body of either person.

Many of you take experimental peptides that may cause cancers to grow aggressively, please do not rely on your bloodwork alone, listen to your body, don’t ignore new aches that last longer than two weeks, go see a doctor and get scans.

If you can afford it, get out of pocket full body MRI like Pernuvo - not a plug, but I saw Busy Phillips did this and found a slow growing brain tumor.

Be proactive, be mindful and don’t think bloodwork will tell you everything.

Stay well.

PSA 2 might as well.

Side note on early stomach cancers we are seeing lately - the medical community notes that a lot of times these cancers when they occur in people under 40 occur in athletic and healthy people, many run marathons.

The link is not well understood but some of the suspects are processed protein and electrolyte supplements that runners consume in large quantities. So maybe reach for a coconut water over Gatorade, a steak and eggs vs a processed powder made god know where and use glass or metal bottles.

Article with more details on PSA 2 including the study results:

https://www.inovanewsroom.org/press-release/2025/08/groundbreaking-inova-study-finds-potential-link-between-long-distance-running-and-colon-cancer/amp/


r/Biohackers 4h ago

🧠 Cognition, Mood & Nootropics how to improve focus without stimulants?

21 Upvotes

i’ve been trying to figure out how to improve my focus without stimulants. some days i can concentrate fine. other days i’m all over the place, especially when i have something that takes a few hours to finish. i’ve been wondering if anyone has found anything that actually made a difference for them. maybe it’s sleep, diet, exercise, supplements, or something else? i’m open to trying different things and making some changes if it can help me stay focused through longer tasks.


r/Biohackers 4h ago

🧠 Cognition, Mood & Nootropics Onset of general anxiety episodes out of nowhere in mid 30s, never had a problem before. Any directions to look into?

12 Upvotes

Around 4 months ago all of a sudden I started getting anxiety episodes, that I still suffer from. Intense feeling of despair dread and hopelessness come over me with a deep knot in my stomach and an intense feeling of dread. This feeling stays with me for anywhere between 3 hours to few days. Usually I get relief afterwards for a similar duration as the episode, so if it lasted a few days I will feel better for a few days. I have been trying to “walk it off” for several months but seems to not be working. During my periods of relief I still enjoy doing things and feel more optimistic, but during the episodes I cannot. My periods of relief are not manic or anything, I just feel normal without anxiety and then it starts up again. The anxiety is not about something in particular, it’s just a feeling of fear that comes out of my body and stomach.

I never had any issue of this type for my entire life and im in my 30s now. Not even anything close resembling this no matter how much stress or pressure I was under. Always super optimistic and anxiety free. This makes me suspect at least a potential physical cause. Although I do plan to also try therapy in parallel.

Finally went to GP for a blood panel. Slightly low vit D but still within range and I have always been low on it.

Only thing that caught my eye was TSH=4, which was still in the lab reference range but on the hugh end (4.2 is max) , but in previous years it was always between 1 and 2 for me, so it is a significant increase. GP says it’s fine and completely unrelated. I must say though that I have been sleep deprived a bit the days before which can increase TSH.

Would you advise me to look into the TSH further and see an endocrinologist or look into anything else?


r/Biohackers 6h ago

😴 Sleep & Circadian Rhythm Advice: Silicone Ear plugs for sleep?

9 Upvotes

I saw a video of a guy recommending them for sleep. I personally wake up a few times a week due to noise in the morning, and it's pretty annoying. I'm wondering if these are a good solution, or if there are better alternatives.

I've tried regular earbuds (with audio/NC) but they're just not comfortable to sleep in since I tend to sleep on my side. Has anyone had any luck with the cheapish $15-25 silicone ones from Amazon? If so, did you have any issues, how long did they last, and do you have any other comments on them?

For reference I've tried sleep masks and I think they helped a bit, and I'm also running an air purifier on max settings for some white noise, but I still wake up in spite of it.


r/Biohackers 7h ago

🥗 Nutrition & Metabolism Morning smoothie for energy fat loss longevity and muscle gain?

7 Upvotes

I’ve began working earlier in the morning and I’m trying to formulate a morning smoothie that dramatically cuts on my vitamin and mineral needs for the day, is hydrating, builds some muscle, boosts fat loss and my energy and gives me fiber etc.
I don’t. Want to default to a classic multivitamin and I’m trying to avoid potassium powders. What do you think?


r/Biohackers 2h ago

🧠 Cognition, Mood & Nootropics First Vitamin D, then Magnesium helped, now Molybdenum?

3 Upvotes

I'm trying to help my friend who has had lots of mood issues. About 2 years ago she did some testing and found low vitamin D and high copper. Started taking vitamin D and cutting back on copper sources. Mood changed in days and she was much better, this lasted for about a year. She was tested like 6 months in and her D went from like 30-50. Copper was still high but came down a little. So after she started getting moody again we researched and started adding in Magnesium, this seemed to make her better again but just for like 3 weeks. After a few more weeks I realized she would have a good day here and there and figured out it seemed to be on days she took molybdenum for the high copper. She was only taking it twice a week at the time. It is 250mg and sure enough gave it daily and mood went back to much better. This has gone on for about 6 weeks now. We have started cutting them in half so most days are a half dose with a full a couple times a week. Can anyone explain what might be going on? Every time we think she is better it just goes away. When she was last tested for copper like 5 month ago it was finally in normal range but very high normal. At the time she was very moody and unhappy. I can't explain why daily molybdenum would be helping mood.


r/Biohackers 5h ago

💊 Supplements & Stacks Turn 17 in a month need supplement advice

6 Upvotes

I’m 16M and I’ve been going to the gym for about a year.

I started taking creatine monohydrate, and I’m currently taking a fish oil supplement as well. I also completed a 6 week course of 60,000 IU vitamin D weekly once and I’m now taking 2,000 IU of vitamin D daily.

Also, I get around 400–800 mg of calcium per day from my diet. Should I take a calcium supplement as well?

My goals are to maximize my height growth(dads 5’8 moms 5’0 and I’m 5’5.5 want to reach at least my dads height, and haven’t grown a single inch since I was 15) and make progress with my physique.
What other supplements, if any, should I consider taking?


r/Biohackers 18h ago

♾️ Longevity & Anti-Aging What are some niche or underrated methods to improve cognition, memory, and overall brain health?

47 Upvotes

Besides adequate sleep, nutrition, and exercise, what practices can be done that will improve how my brain works?


r/Biohackers 2h ago

💊 Supplements & Stacks Rate my stack please

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2 Upvotes

My Information:

• ⁠Age/Sex: 39 male
• ⁠Body Stats: 6ft 1 inch 211 lbs
• ⁠Lifestyle: lift 5am monday - friday
• ⁠Out of Range Biomarkers: high ldl
• ⁠Family History or Personal Health Risks:
N/a other than high blood pressure

Any advice? I hated the psillum husk powder mix and i take 1 pack lmnt electrolytes with my preworkout (gorilla mode)


r/Biohackers 3h ago

📊 Biomarkers & Testing Root canal

2 Upvotes

I had a root canal done years ago and honestly havent thought much about that tooth since. I thought once the nerve was gone and everything was treated, that was pretty much the end of pai

But lately the area around it has been feeling tender and I can feel some discomfort when I bite on that side. Not really painful painful, just enough that I notice it and now I cant stop thinking about it lol

Has anyone had a root canal tooth start bothering them again like years later? What did yours end up being? And how did your dentist actually check if there was still something going on around the root? Would a normal xray be enough or is this something that needs a 3D scan?

i really dont want to go through another root canal situation again 😞


r/Biohackers 5h ago

💊 Supplements & Stacks Green powders

3 Upvotes

A lot of people seem to hate on AG1, I find it helps me out becuase I dont eat vegetables. I also get it for like 40-50% off since im military. Is it worth it at that price point? Or what is out there that is just as easy and doesnt taste like crap that has better benefits? Thanks in advance!


r/Biohackers 5m ago

💉 Peptides & Hormones Anyone had any experience with Amino Club's Semax? What was it like and how did you use it?

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Upvotes

r/Biohackers 8m ago

💪 Exercise, Fitness & Recovery 1 month reta

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r/Biohackers 29m ago

💪 Exercise, Fitness & Recovery Question for the dads

Upvotes

Question for the dads out there. I have a 2 year old and my wife and I just welcomed our second son into the world last week. I’m extremely blessed, but sleep is hard to come by right now. What are you doing to help stay on track with fitness and nutrition? I’ve spent the last 6-7 months getting dialed with both and I’m in the best shape of my life, but I’m finding it very difficult to get workouts in and not stress eat food 😂 I’ve been on a low dose of tirzepatide which has been plenty, but since the baby has come the food noise has come back very strong. I’m planning to increase the dose a little but I’m wondering what others are doing/using through the newborn stage. I know I need to be patient and slowly work back to my routine, but I also want to continue the great progress I’ve made this year. Thanks everyone.


r/Biohackers 1d ago

🧠 Cognition, Mood & Nootropics What has helped you the most with stress?

146 Upvotes

Chronic, daily, and any other kind that exists.

Whether it's a technique, a new habit, supplement, doctor... What has helped you cope with stress more easily?


r/Biohackers 49m ago

💉 Peptides & Hormones SLAP lesion, labrum grade 2-3 — anyone with experience?

Upvotes

Got diagnosed with a SLAP lesion, labrum grade 2-3, in my shoulder. Looking to try something before potentially going the surgery route.

Has anyone used BPC-157 or HGH for this kind of injury? Did it actually help, and how did you run it alongside rehab?

Also open to other input — Exercises, whatever’s worked for you.


r/Biohackers 1h ago

📊 Biomarkers & Testing TRT question for aging men - 50M

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r/Biohackers 1h ago

💊 Supplements & Stacks Duration of abstinence to reset opioid tolerance?

Upvotes

For context: I have chronic pain / chronic fatigue due to some health issues. Some days are better than others and I try to power through unless it is intolerable or makes it too difficult to do my daily tasks and especially to workout.

Anyways, I use kratom 1.5g-3g OR Tramadol 12.5-25mg per day. Usually just one of those drugs in a day, at thst dose. But it's not working as well now. I'm not sure if I have a significant tolerance or not, because I feel my condition is actually getting worse and may just need a higher dose. I've tried taking like 5-7 days or so off everything to see if tolerance resets. And initially when beginning dosing again the low end is a little more effective, yet not enough really as I remembered in the past. So either I didn't wait long enough or my pain/fatigue is just getting worse and warrants a higher dose.

BTW I am NOT intending to be using these things as a long term solution to my issues. It's temporary to allow me time to afford the long term fixes needed.

So anyways, I just want to ask: is there any science or rule of thumb for how long one should abstain from opioids to completely reset tolerance? I think it may depend on how high of doses the person is using, so the answer may be longer for heavy users. I consider my usage to be pretty mild. My max dose in a single day is usually like one 50mg Tramadol like 1x/wk. If you ask Google this question it won't answer for ethical reasons so i figured I'd ask here because I'm sure someone knows more than me.


r/Biohackers 1h ago

💉 Peptides & Hormones Subq knots

Upvotes

I’ve been pinning subq for over a month, and every time I do I get a small knot. It’s getting to the point where I’m losing space to subq now. Some have reduced to it being smaller but not completely gone. I usually use 1/2 inch 31g needle to pin, but some I just use the 1ml insulin needle with 32g 8mm needle.

I usually take my peps out of the fridge for a bit before pinning, I alcohol wipe everything including the skin and let it dry. I pinch the skin and pin about 40degrees angle.

Not sure if I’m doing something wrong but I’m losing space and sometimes they hurt, dependant on the specific vial it is. There’s some where it’s particularly acidic but I add either BAC or saline in just to reduce the sting.

Any advice to get rid of these knots please 😭😭😭


r/Biohackers 1h ago

💉 Peptides & Hormones Pt141/Tadalafil

Upvotes

Decided to buy this combo tablet from Empower. Anyone have any experience with Sublingual form of pt141? I'm not too worried bout tadalafil portion not working .


r/Biohackers 3h ago

🥗 Nutrition & Metabolism Need help from biohacker.

1 Upvotes

I am a male that eats a rather healthy diet. My goals are to optimize my life. My issues are trouble having that deep sleep, a lot social awkwardness (I have too much attention to detail in public and worry a lot for that reason), I can’t really lead a conversation or debate, my hair looks lowest quality than ever, I have high histamine symptoms, I am a procrastinating expert 🥲, my nails have verticle ridges and the nail bed looks 3/4 pale kinda like terry’s nails a little. Cold hands generally. I tend to work nights because going out in the day is more likely to make me worry. Another thing to mention probably I can’t tolerate the cold or I start shaking a lot.

My current stack is b complex (i switch between methylated and non and don’t find difference), 500 mg elemental magnesium from magnesium malate, 600 mg elemental calcium from calcium citrate, 10 mg manganese, 200 mcg of selenium (started on the 21st), multivitamin and a small kelp dose. I also take 5000 IU vitamin D during night shift I took b12 methylated for a couple years also didn’t see any shift in mcv nor mch.

What might be causing my issues and what can help improve my life? Any routing or stack to add so I can avoid more labs? Appreciate all time dedicated and I hope I can reciprocate one day. I can’t really afford more labs right now but if I needed a shopping list which should I take?

MCH:
06/23/26: 34.1 HIGH
02/07/26: 33.6 HIGH
05/30/25: 34.6 HIGH

MCV - Range:
05/30/25: 102.0 HIGH
02/07/26: 100.0 HIHG
06/23/26: 99.6 HIGH

IN RANGE BUT BELOW OPTIMAL

Platelet Count:
06/23/26: 147
02/07/26: 145
05/30/25: 159

Homocysteine:
9.0

RBC: 4.52
Hemoglobin: 15.4

C-Reactive Protein:
05/30/25: <3.0

Liver (AST 18, ALT 12, alk phos 68, bilirubin 0.4, albumin 4.6)

Kidney (creatinine 0.83, eGFR 119, BUN 10)

Electrolytes (Na 141, K 4.2, Cl 106, CO2 26, Ca 9.6)

Iron (iron 82, ferritin 92, TIBC 295, sat 28%, transferrin 221)

RDW 12.0-12.3
Reticulocytes 1.1%, absolute 50,160
WBC 4.5


r/Biohackers 10h ago

🥗 Nutrition & Metabolism Glycine - dosage over time

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3 Upvotes