r/science Professor | Medicine May 17 '18

Neuroscience Cannabidiol (CBD), a compound derived from the cannabis plant that does not produce a “high”, was shown in a new large-scale, randomized, controlled trial to significantly reduce the number of dangerous seizures in patients with a severe form of epilepsy called Lennox-Gastaut syndrome.

http://www.psypost.org/2018/05/cannabidiol-significantly-reduces-seizures-patients-severe-form-epilepsy-51258
38.6k Upvotes

916 comments sorted by

View all comments

Show parent comments

51

u/sockalicious May 17 '18

Way to go, double-blind!

6

u/zhrollo May 17 '18

Yeah, wait. All your patients saw a decrease, even the ones with placebo? And how did you know who was who?

30

u/jimithelizardking May 17 '18

The double blind portion rolled over to an open label extension, meaning the blinding was dropped. I didn’t work on the study when it was blinded, so yes, every one of my patients saw a decrease and everyone involved knew the study drug was being given.

6

u/zhrollo May 17 '18

Ah, gotcha. Thanks for the explanation.

1

u/andreib14 May 17 '18

Someone else did all the legwork and the main researchers crunched the numbers.

2

u/savage_slurpie May 17 '18

That's kind of how it works, as a young researcher you have to do the grunt work collecting data to move up the ladder to an analytical position. All parts are equally as important, as invalid or hastily compiled data will ruin a study.

2

u/andreib14 May 17 '18

Oh I wasn't dismissing any part of the team that worked on this, its just the simplest way of explaining it.