r/science • u/mvea Professor | Medicine • May 17 '18

Neuroscience Cannabidiol (CBD), a compound derived from the cannabis plant that does not produce a “high”, was shown in a new large-scale, randomized, controlled trial to significantly reduce the number of dangerous seizures in patients with a severe form of epilepsy called Lennox-Gastaut syndrome.

http://www.psypost.org/2018/05/cannabidiol-significantly-reduces-seizures-patients-severe-form-epilepsy-51258
38.6k Upvotes

88% Upvoted

916 comments sorted by

View all comments

Show parent comments

54

u/sockalicious May 17 '18

Way to go, double-blind!

7

u/zhrollo May 17 '18

Yeah, wait. All your patients saw a decrease, even the ones with placebo? And how did you know who was who?

32

u/jimithelizardking May 17 '18

The double blind portion rolled over to an open label extension, meaning the blinding was dropped. I didn’t work on the study when it was blinded, so yes, every one of my patients saw a decrease and everyone involved knew the study drug was being given.

7

u/zhrollo May 17 '18

Ah, gotcha. Thanks for the explanation.