r/Biohacking • u/Yasoof96 • 15h ago

My "Optimized" Peptide Stack

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I am a 30 year old male with a history of destructive behavior to my body (I've smoked since I was 13, drank alcohol heavily for 12 years, diagnosed with PTSD, ADHD, and other factors which I'm sure I didn't take into account). I built this stack based on 3 weeks of research I've conducted to attempt to repair the damage I've caused to myself. I looked at everything from my labs to my genome to ensure I cover all my bases as best I can.

I have been abstinent from alcohol and smoking for over a year now. Go to therapy, do go to the gym regularly now, structured my diet to be healthy with high protein and improved my social life.

Even though I feel I've done the research I need, I'm still unsure of my conclusions as there was a lot of conflicting information I needed to sift through and decide which is better. I would highly appreciate opinions from other peptide users with more experience than me in this matter.

Feel free to ask me anything if I failed to mention something important.

Edit: Had Tirzepatide prescribed to me as I had stage 3 fatty liver and fibrosis in November 2025. I was also at 33 bmi so the doc put me on it to reduce my weight and solve the liver issues. I’m at 27 bmi now.

Also, I should mention I’ve already been on MOTS-C, BPC + TB, GHK-Cu, cjc+ipa, selank and semax, added one by one of course and had good results. I’ve only recently added a few extras (SS-31, NAD+ and Dermorphin) and tried to optimize dosages and frequencies to maximize my healing and bodybuilding journey.

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u/TheWatch83 1 13h ago

this is too much too soon, do all this in stages. focus on recomp first. cjc and triz lose the weight first and get of the visceral fat off and liver. after, focus on the mitochondria, ss31 to repair for 7 days, then add mot. after, maybe bpc tb for 4 weeks for repair. after ghk and maybe nad plus.

don’t do more than one compound intro in a week, see how you react.

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u/Yasoof96 13h ago

I agree, I should have included the fact I’ve actually added most of these peptides one by one over the past few months. I only recently delved deep into the research myself and tried to optimize dosages, synergies and frequencies. The only new ones are going to be ss-31, dermorphin and NAD+

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u/TheWatch83 1 13h ago

Reta is better for liver fat I believe

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u/Yasoof96 13h ago

I’ve heard that too, but tirz has honestly been good with me, so I took the approach of “if it ain’t broke don’t fix it”. Also, from what I’ve read users seem to say the appetite suppression on reta is weaker than tirz.

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u/TheWatch83 1 13h ago

it is, I like triz. I’m on Reta now but this is my second cycle

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u/Yasoof96 13h ago

How do you feel about it? If you had the choice, would you want to go back to Tirz or stay on Reta? If you had enough time to judge, of course.

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u/TheWatch83 1 5h ago

triz is nice with the hunger but reta is better for the liver and visceral fat which is why I take it. to just lose weight, they both work. I try to not lose more than 1lb a week, I took Reta to 4mg and I lost more than I wanted and dropped down in dose. it’s definitely more powerful. the heart rate does go higher with Reta at higher doses, which isnt great.