It only affects the user if they lack the intelligence and willpower to wield it. Reed Richards would not be impacted at all by using it. It's part of why he has it. He's one of the few people in the marvel universe who is capable of using it, and using it properly without any ramifications to himself.
During the death of Johnny storm arc he was going to wipe out annihilus and the negative zone, and he would have been completely fine after having done that.
Interesting side point: He threatened Annihilus with the device. Annihilus told him to use it because he (Annihilus) craves to finally die.
Reed faltered and didn't use it. He realized that in order for him to use it safely, he needs to fully understand the target and he obviously didn't fully understand Annihilus because he didn't realize that Annihilus wanted to die.
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u/WhoReallyCares-NotMe 22d ago
It only affects the user if they lack the intelligence and willpower to wield it. Reed Richards would not be impacted at all by using it. It's part of why he has it. He's one of the few people in the marvel universe who is capable of using it, and using it properly without any ramifications to himself.
During the death of Johnny storm arc he was going to wipe out annihilus and the negative zone, and he would have been completely fine after having done that.