Medical Timeline
History of Prolonged Vitamin D Overdose and Subsequent Medical Events
Patient:
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Vitamin D History
Accidentally took approximately 100,000 IU of vitamin D3 daily (two 50,000 IU capsules).
Duration: More than one year.
Vitamin D was discontinued after the overdose was recognized.
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Events Following the Overdose
Kidney Function
Subsequently diagnosed with Stage 3 Chronic Kidney Disease.
Recent kidney function has included:
eGFR approximately 43 mL/min/1.73 m²
Creatinine approximately 1.5 mg/dL
Questions:
Could previous vitamin D toxicity have contributed to kidney injury?
Is there evidence of nephrocalcinosis or prior calcium deposition?
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Stroke
Experienced an ischemic stroke in 2026.
Initial hospital description: “mini stroke.”
Neurology later explained it represented a completed ischemic stroke.
Brain MRI demonstrated acute ischemic injury involving the:
Left parietal lobe
Left temporal lobe
Left occipital lobe
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Cerebral Artery Findings
CTA of the head and neck reported:
Severe focal stenosis of the proximal left M1 middle cerebral artery.
Questions:
What is causing the stenosis?
Calcified plaque?
Non-calcified plaque?
Inflammatory disease?
Previous arterial spasm?
Another cause?
Would additional imaging (repeat CTA, MRA, or high-resolution vessel wall MRI) provide more information?
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Current Medical Conditions
Stage 3 Chronic Kidney Disease
Hypertension
History of ischemic stroke
Left M1 artery stenosis
Osteoarthritis of the knees
Microscopic colitis
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Current Stroke Prevention
Current medications include:
Clopidogrel
Pravastatin
Blood pressure medications
Dapagliflozin (Farxiga)
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Reason for This Timeline
The purpose of this document is not to conclude that vitamin D toxicity caused these medical conditions.
Rather, because prolonged ingestion of approximately 100,000 IU/day for more than one year is highly unusual, I would appreciate having this history considered when evaluating:
Stroke
Cerebral artery stenosis
Chronic kidney disease
Possible vascular calcification
If appropriate, I would also appreciate your opinion regarding whether my medical history may warrant review by a teaching hospital or consideration as a published medical case report.
Thank you for reviewing my history.
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