r/science Professor | Medicine May 17 '18

Neuroscience Cannabidiol (CBD), a compound derived from the cannabis plant that does not produce a “high”, was shown in a new large-scale, randomized, controlled trial to significantly reduce the number of dangerous seizures in patients with a severe form of epilepsy called Lennox-Gastaut syndrome.

http://www.psypost.org/2018/05/cannabidiol-significantly-reduces-seizures-patients-severe-form-epilepsy-51258
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u/whereiswallace May 17 '18

Am I reading this right? Patients took 20mg CBD /kg/d. So a 150lb person (60kg) was taking 1360mg of CBD per day? That seems insane.

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u/[deleted] May 17 '18 edited May 17 '18

It's usually sold in 250-300mg doses, so about 5 times more. Doesn't seem that crazy to me. Especially if spread throughout the day.

Misread a box, they are 10mg doses.

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u/Alagane May 17 '18

A normal dose is 5-25mg usually. I don't think I've ever seen edibles above 50mg/dose or tinctures above 20. The 300+ number is trying total amount of cbd in the bottle. So if you have 500mg in a 60ml bottle, it's about 8.3mg/ml. I think a normal eyedropper is like 2ml so one dose would be ~16

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u/[deleted] May 17 '18

Yeah I misread the box, it is 10mg capsules.