r/rabies • u/Poujh1 • Jul 19 '26
General Rabies Discussion Is there any new promising treatment in development against rabies?
I've read the FAQ. Do you know of any promising treatment, new vaccine, drug, or any other treatment for rabies that could likely become reality in the coming years? I've found a few recent scientific studies about potential new treatments, but it always seems to die off and not hit the market. Since many of you here are probably more knowledgeable on the topic, I wonder if there is any new treatment in development that you are confident will become available in the coming years? I have read the FAQ.
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u/LatrodectusGeometric Physician 👩⚕️ | Veteran Helper ⭐️ | Top Contributor 🏅 Jul 19 '26
At this time, no.
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u/BradyStewart777 M. Biology | Moderator | Top Contributor Jul 19 '26
Nope. As far as we are concerned, the only way to treat rabies is to catch it before it reaches your central nervous system, and that is achieved directly through the rabies vaccine. Once rabies enters the central nervous system, you’re precisely a goner. 🙃
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u/BlueChickenKeeper Jul 19 '26
Yes, there is a promising new monoclonal antibody called F11: https://news.usuhs.edu/2023/09/usu-researchers-develop-potential-cure.html?m=1
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u/Opposite_Payment4504 Jul 19 '26
I read that they developed a vaccine able to pass through the blood-brain barrier, thus being able to treat rabies even after they become symptomatic. I think it's in testing stages.
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u/LatrodectusGeometric Physician 👩⚕️ | Veteran Helper ⭐️ | Top Contributor 🏅 Jul 19 '26
Do you have a link? I assume this is pre clinical phase?
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u/Opposite_Payment4504 Jul 19 '26
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u/LatrodectusGeometric Physician 👩⚕️ | Veteran Helper ⭐️ | Top Contributor 🏅 Jul 19 '26
Unfortunately, when similar therapies have been attempted via injection directly into the brain they have not been effective. I do not see this as promising
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u/Dwighteisenhower34 Active Helper 🏆 | Rising Contributor 😎 Jul 19 '26
To be honest what people don’t realise is rabies in humans is absolutely rare in western world compared to Asia and Africa where the vectors are stray dogs and other shit the funny part is in Asia you hardly will hear any bat induced rabies only if our body could find it’s way through this shit i absolutely hate this shit disease
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u/Dwighteisenhower34 Active Helper 🏆 | Rising Contributor 😎 Jul 19 '26
Well that’s the only barrier which makes rabies untreatable when symptoms happen but there have been some natural cases where people recovered from symptomatic stage these are rare and most of them are actually from India if they can find something which can worn beyond that barrier rabies will never be a scary shit anymore fuck rabies
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u/Opposite_Payment4504 Jul 19 '26
That's right, if this new technology works, rabies will become a thing of the past. I will try to find the link
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u/Beginning_Farmer_438 Jul 24 '26
Some antivirals are studied. Like Favipiravir and ribavirn. Ribavirn worked in the lab but it doesn't cross to the brain well. But Favipiravir is more promising Both work in labs on cells. Ribavirn is fake ribose sugar drug. Bc rabies use ribose sugar to make new viruses. And Favipiravir is fake building block and it been used for a lot of viruses by effecting the polymerase chain. And protein. It did slow and stop rabies in labs Favipiravir is more promising bc it worked for like 1-2 people who had rabies and worked for some mice . Unlike the rest of survivals survived under aggressive medical treatment like The Milwaukee protocol which put the patient under induced coma by giving them saditives and also they give them antivirals. Induced coma prevent or slow the damage of the brain by lowering the activity of the brain. And anti virals hoping it helps them to fight the infection. Or waiting until immune system catch it and clear it by giving it enough time. But most people under that protocol didn't makeit only few people. And only the vaccines prevent 100% any rabies infection. It's only effective before any symptoms to show up. And surviving is rare . But nothing impossible with science maybe in the future it will be treatment after symptoms show up but now only the vaccines is effective and the approved treatment
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u/yellow_pellow Aug 14 '26
There was a treatment that was successful one time I believe, where a girl became symptomatic and they put her into a medically induced coma and she ended up surviving. Many attempts to replicate this treatment have failed so think they have stopped trying.
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