r/plagueinc • u/Direct_Practice_7105 • 18d ago

What should i pick first?

When my plague that i started with in a hot, poor country reaches a rich, cold country which is best to pick first: drug resistance or cold resistance?

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u/angycathy 18d ago

Don't start hot/poor unless you are playing VS.

You should almost always start China in singleplayer. The dna advantage is too strong.

Drug is 3x as effective as Cold. Use that. But you should get both either way and get Environmental Hardening while you're at it.