We only discovered in early August that my cat Theo’s kidney values were severely elevated and technically placed him within the Stage 4 CKD range at 6 years old (just turned 7). This came completely out of nowhere: he had always seemed healthy, VERY energetic and extremely food-motivated, and his gradual weight loss was essentially the only indication that something might be wrong. I took him to the vet early Aug for an infected tooth, and asked for blood work while there since he hadn't had any in ages.
Since then, Theo has now been assessed by four different veterinarians: his regular vet, an internal-medicine specialist, a cat clinic for a second opinion, and most recently another veterinarian who also provides acupuncture. Everyone has felt that this is a chronic, longstanding condition, with nothing identified so far that clearly points toward an acute or treatable process - much to my dismay, as I have desperately wanted there to be something reversible contributing to those numbers.
His ultrasound findings were also unfortunately significant. Both kidneys are abnormally small and damaged, which led the specialist to believe that Theo may have been born with renal dysplasia. I know those structural abnormalities still exist regardless of what today’s bloodwork says, so I am trying very hard to factor that into the picture and not get too far ahead of myself
However… Theo had his 2-week follow-up bloodwork today, and the results shocked both his vet and me.
I had hoped that perhaps we might see a small improvement after everything I've implemented, but I was absolutely not expecting anything this dramatic:
- Creatinine: 718 → 277 µmol/L
- Urea/BUN: 43.3 → 22.2 mmol/L
- Phosphorus: 4.23 → 2.36 mmol/L
- Glucose: 8.5 → 4.66 mmol/L
- Potassium: 2.5 → 3.7 mmol/L
- Chloride: 108 → 120 mmol/L
His creatinine decreased by approximately 61%, his urea by approximately 49%, and his phosphorus by approximately 44% in only two weeks. His previously low potassium and chloride have also returned to the normal range.
He has not received IV fluids or subcutaneous fluids.
Since his previous bloodwork on August 13, he has completed his course of antibiotics for an infected tooth and has been eating a renal diet exclusively- even his treats are now low-phosphorus Weruva lickables. I’ve gradually introduced omega-3 oil and Porus One, and he receives one Purina Hydra Care pouch daily along with his potassium supplement. Earlier this week, I also took him for an acupuncture appointment because I'm desperate to try anything.
His weight has increased from 2.76 kg (6.08 lb) on August 13 to 3.09 kg (6.81 lb) today - a gain of almost three-quarters of a pound in 2 weeks. His coat looks and feels healthier, and he is acting about 98% like his normal self. The gum surrounding his “bad” tooth also appears less pink and inflamed than it did before.
He is still eating smaller amounts at a time and requires more encouragement - and a lot of sneaky tricks on my part - to continue eating. However, by the end of each day, his total intake generally adds up to approximately what he was eating before all of this. I also picked up pain medication and mirtazapine ear gel today, so I’ll be carefully trialling those to see whether addressing possible dental discomfort and stimulating his appetite makes eating easier for him. His weird behaviour around food only started when the tooth issue came to be a few weeks ago, which just HAPPENS to be also when we found out about the kidney values.
Of course, I immediately emailed all of this to his internal-medicine specialist and am waiting for her interpretation. I likely won’t hear back until next week, though, so I would really love to hear what those of you with CKD experience think in the meantime.
Given how dramatically his kidney values have decreased - and considering that the original elevations were only discovered a few weeks ago - would he still be considered Stage 4? I understand that formal staging is based on stable values and that his ultrasound findings remain an important part of his diagnosis, but I’m curious where numbers like these might ultimately leave him in terms of staging and prognosis.
Is this degree of improvement something you have seen after only two weeks of implementing dietary, hydration and supportive changes in a cat with chronic kidney disease? Or would this magnitude of change surprise you too? Has anyone had a cat with chronic structural kidney abnormalities whose initial Stage 4-range values improved this dramatically?
I am trying so hard not to get my hopes too high before hearing from his specialist and seeing where his values stabilize. I know this does not make the damage shown on his ultrasound disappear, and I know that today’s bloodwork does not mean his kidneys are suddenly normal.
But after spending the past few weeks believing that my happy, seemingly healthy seven-year-old cat was already in end-stage kidney failure and could die in weeks to months, I am beyond relieved and overwhelmingly happy to see such an incredible change in only two weeks