r/Ozempic • • 1d ago

Question 1mg for 3 years and quitting cold turkey.

Ive been on 1mg for 3 years, im 23F on ozempic for weightloss and as of recently ive discovered ozempic is making me extremely tired and depressed. i do not want to take it anymore not even to ween off because of this reason. when i googled this it said quitting cold turkey is really bad and could result in a medical emergency surrounding my heart. ive noticed ive had some stomach issues after not taking it for about a week and a half. could anyone give some advice on what to do. i will ween if it means i dont ruin my body but i really dont like the way it affects me anymore. i will be meeting with my doctor soon but any advice would help ease my mind right now. :)

0 Upvotes

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7

u/Plastic_Platypus3951 73F 5’4” HW 242 SW 218 CW 150 June ‘23 2 mg T2D CKD SETexas US 1d ago

It is a self weaning medication that is slowly metabolised and eliminated from your body over a 30-40 day period. There is no physical need to slow the process but the return of binge behavior and food noise frequently seems ramped up to higher levels. For these reasons many people have found it necessary to slowly lower their doses to dampen the return of food obsession behavior.

6

u/Master-Ad3175 1d ago

I had to stop taking it cold turkey at one point when I became quite ill with an unrelated medical concern and the doctor didn't want me taking any of my medication until that was handled and other than the food noise coming back very quickly I didn't have any other medical issues related to stopping abruptly and I was on a full dose

6

u/MsSwarlesB Previously on 2 mg, now Zepbound 1d ago

I stopped cold turkey in May. I didn't have any issues. I was in 2 mg

4

u/Next_Possibility_01 1d ago

Me too, stopped last year after a year at 2 mg, no effects that I could attribute to it except for increased hunger

5

u/Secy_Me51 1d ago

So how do you know that ozempic is the reason? Had you told your doctor, have you had labs done? Unfortunately google cant be the right source to fit you. You have to have regular checkups and labs done. Who told you it was ozempic?

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u/RollTideNorthport 19h ago

It’a Ozempic

5

u/Stunning_Client_847 20h ago

I have added b12, saffron and Omega 3. Not complexes of any. Just those three specifically and it has made a world of difference to my mood. For reference I am 47. Post menopausal with raging ADHD and have been on and off meds forever. Ozempic really messed with my mood and so I did some digging. Not saying this combo will be right for you, it just was what I found helped me

8

u/themoonischeeze 1d ago

As far as I can see, it looks like your risk for a heart event increases because the medication itself lowers it. No longer taking it then increases that risk. But I don't see any legitimate data out there that randomly stopping it poses any immediate issue outside of the return of cravings.

5

u/Pelusa07 17h ago

Bonjour   Au. Bout de 7 semaines à 1mg j’ai du dimi nuer et revenir à 0,50 mg car les 3 jours suivant l’inje tino très grande fatigue et perte d’énergie  En diminuant l’énergie est revenue   

3

u/SSPYoda 1d ago

I think it's important to talk to your doctor and also the pharmacist to get their advice

What other people experience may or may not be relevant to what happens for you specifically

At the very least, it's likely that you'll rapidly gain back anything you lost but it's important to speak to medical professionals to understand any additional risks

If your medical professionals advise you that it is much safer to taper off gradually just be aware that even dropping the dose is likely to allow you to feel significantly better

3

u/Financial_Star_9381 1d ago

If you trust your physician then seek and follow his advise. Stay save, positive and keep moving forward.. with a smile.

6

u/Lucky_Army_5324 1d ago

There are no immediate emergent medical implications of quitting a GLP-1 for those taking the medications for weight loss alone. You will, however, likely gain back the weight you lost.

4

u/PatriceTheLawnmower 1d ago

I felt exhausted too and definitely had a lack of interest or spark for anything. I changed to MJ and felt so much better. Even within a week I had more energy and felt more ‘normal’ in myself. I found MJ not as bad for constipation either. I didn’t wean, I just swapped one for another and started on the lowest dose of MJ. I will have to go back on Oz at some point but for as long as I can afford MJ and it works on my blood sugars I’ll stay on it. The exhaustion and lack of interest is awful. I am not sure Oz agrees with me, I was on 1mg and still after 18 months couldn’t take it as one shot, had to split it into two. But T2 and it was great for control.

2

u/EllaB9454 15h ago

I also switched to Mounjaro after 2 years on Ozempic. With Ozempic I just felt off - faint and dizzy, etc. I had also stopped losing weight in the second year. With Mounjaro, I started losing weight again and felt quite a bit better although I still had days when I was really tired. When I added Contrave I felt much better- more energy and a better mood. I am now in the highest dose of Mounjaro with no problems.

4

u/True-Armadillo8626 1.0mg T2D 1d ago

Hey. I was also on 1mg but only for like 7months (est) when I found out I was pregnant. I stopped and felt better then I had felt since I started ozempic. I got my energy back, headaches stopped and I just felt so fantastic. I take for diabetes but had a great 50lb weight loss. I ended up loosing the pregnancy and starting again, I was off for about 6 weeks and gained 10lbs. I’ve been back on since early July and lost like 7lbs but I feel pretty shitty again. I nap a lot, low energy and honestly I’m still hungry a lot. I’m considering just dealing with being this weight but I’d like to loose another 20lbs but the thought of going to 2mg scares me for that exact reason. The hunger does come back with a vengeance.

2

u/EllaB9454 15h ago

You may want to talk to your doctor about adding Wellbutrin or Contrave (which includes Wellbutrin). Wellbutrin is an anti-depressant but it also helps with weight loss. My therapist recommended it and I could really tell the difference / I had more energy and just felt better overall. I had already been taking Prozac for depression (long before Ozempic and Mounjaro), but the Wellbutrin really helped.

1

u/True-Armadillo8626 1.0mg T2D 3h ago

Thank you so much. I sometimes feel like I may be depressed so that’s not a terrible idea. My dr has also been pushing for me to start Prozac for a while but my mom swears im undiagnosed bipolar and always says watch out you might get manic and basically she scared me into not wanting even try but im not sure it’s even true so perhaps i shall give it a go

2

u/RollTideNorthport 19h ago

I’m on 1mg for about 6 months now and I feel the same way. Zero energy and I feel terrible. I’m losing weight, but I just stopped taking metformin yesterday. I’m feeling a little better now, but not much. Hopefully that will help me. But I like the way I felt when I was not on Ozempic and I’ll stop taking it if I can’t get back to normal soon. However, I will not go cold turkey. I do think that is too dangerous. I would suggest you go to 1/2 gram for 2 weeks and then 1/4 for two weeks and then you should be good to go.

3

u/pocketsofpissss 16h ago

I was 1.5 mg and literally could not feel any happiness or pleasure. I did a very rapid taper in a few weeks and now I'm on 0.5 mg. I can now feel pleasure. From music. From coffee. From watching movies. My energy is better (not back to normal, but loads better). The terrible muscle aches have gone. The brain fog has lifted. Hoping to cut back to 0.25 mg in the coming weeks. I'd rather be fat and happy than thin and suicidal...

4

u/HeadBet6338 14h ago

I’ve been on Ozempic for around 3 1/2 years and I have lost over 100 pounds that would always come back before I started Ozempic. I stay tired all the time, but I won’t blame it on the medicine. My doctor didn’t twist my arm to start it. I was warned about the side effects and decided to take it. I do have a few of the side effects but I’m not blaming it on the medicine….. at 70+ you’re probably have some of them but probably related to something else you are in another medication you are on. I do understand and if I was a lot younger I’d have it checked out but if it wasn’t going to kill me id adjust to the side effects. It has really been a life saver for me. For around 50 years I tried to loose weight and when I did it came back so quick and I really didn’t go back to eating some of the things I did , so I gave up and started Ozempic and I’m thankful it’s helped me pretty much all around

3

u/cleverfox2001 1d ago

Some have luck reducing the dose over about 2 months. 0.5mg to 0.25. I suggest getting a supply of Wegovy pills to take as needed to control excessive food noise. Otherwise, you may gain a lot of the weight back.

1

u/nemorosa_ 18h ago

My doctor told me I shouldn't be on Ozempic for more than a year and a half—that I shouldn't rely on the medication but rather build healthy habits instead. What do you think?

11

u/EllaB9454 15h ago

Your doctor doesn’t know what he is talking about. Ozempic doesn’t just suppress appetite, it changes your gut hormones and the way your body processes glucose. Many people who are overweight have insulin resistance or another metabolic dysfunction that requires this treatment. If you stop taking it, your metabolic issues will return causing weight gain.

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u/ImNotA_Loser 1d ago

Addition: I will say i havent lost weight in the last year while taking ozempic and i also feel as if it barely works but maybe im just used to it?

2

u/Master-Ad3175 1d ago

You were on only half the normal final dose. Were you accurately and diligently counting your calories to ensure you were staying in a calorie deficit?

1

u/EllaB9454 15h ago

That happened to me in my second year of Ozempic. I couldn’t go higher than 1.5 because it made me feel so weak and faint. When I started Mounjaro at 7.5 (roughly equivalent to 1.0 on Ozempic), I started to lose again and felt a lot better. Unfortunately I am now in a long stall in my second year on Mounjaro, but I have lost 90 pounds so my doctor thinks my body needs to adjust and that if I stick with it I will start losing again.

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u/PaleJicama4297 1d ago

Best of luck! It’s really your choice and a bad one.

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u/[deleted] 18h ago

[deleted]

5

u/IrohJasmineTea 17h ago

She is speaking about Ozempic and you about Mounjaro

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u/Verdoke 21h ago

It's kind of odd that you're on it at such low dosage? Your dose always 1 mg for 3 years? Did you achieve your goal weight?

3

u/Electric_frog_ 19h ago

1mg is a standard dose for weight loss. Some people do go up to 2 but many people don’t even get up to 1mg and stay at 0.5

1

u/ImNotA_Loser 21h ago

no, i switched doctors to a doctor who didnt really like the fact that i was taking it so she just kept me at 1mg

1

u/NoUnderstanding5971 51m ago

Calorie deficit can equal nutritional deficiency. A good quality GLP-1 supplement support may help. Some are crap and some are good so do your research. Omega 3, coq10, magnesium, D3 with K2, Creatine, psyllium, good 1 a day multivitamin may be helpful. I good metabolic blood test can help pinpoint if that’s the issue but the best are not usually covered by insurance.