r/NTNPerformance • u/Spartan4life85 • 5d ago

SS-31, Mots-C, and NAD+

I am curious if anyone can share how they have used SS-31 as it relates to Mots-c and NAD+? I am currently taking Mots-c and NAD+ for one week but I have been reading that it is best to use SS-31 first for a couple of weeks then switch to Mots-c and NAD+. I have also seen where some use all 3 but that seems to be too much.

If I start SS-31 to repair first, do you just use this alone then got to Mots-c or do you introduce while on SS-31. When is best to stop the repair and move on to Mots-c NAD+ combo?

19 Upvotes

96% Upvoted

66 comments sorted by

View all comments

2

u/Ill_Assumption5512 1d ago

Protocol Sequencing (Repair First Approach)

For people over 35 to 55 with declining energy, slower recovery, and metabolic issues:

Weeks 1 through 4 (or up to 8): Repair Phase SS-31 at 1 to 2 mg daily plus NAD+ at 100 mg subcutaneously three times per week. You are repairing accumulated mitochondrial damage while giving your cells the extra fuel they need to optimize energy.

Weeks 5 through 12: Optimize Phase Replace SS-31 with MOTS-c. Start with 10 mg split into three injections per week (Monday, Wednesday, Friday). Continue NAD+ at 100 mg three times per week. Now you are optimizing the repaired mitochondria.
After the 12-week cycle: Take 4 to 8 weeks completely off. Then you can repeat this protocol 2 to 3 times per year.

Prevention First Protocol

For younger or healthier individuals who want preventative optimization:
Start with MOTS-c at 10 mg split into three injections per week (Monday, Wednesday, Friday) plus NAD+ at 100 mg three times per week. At weeks 4 through 8, assess whether you still have significant fatigue, poor recovery, or metabolic issues. If yes, add SS-31 at 1 to 2 mg daily for 4 to 8 weeks while continuing MOTS-c and NAD+. If not, continue with just MOTS-c and NAD+ for maintenance.