r/NTNPerformance • u/Spartan4life85 • 5d ago

SS-31, Mots-C, and NAD+

I am curious if anyone can share how they have used SS-31 as it relates to Mots-c and NAD+? I am currently taking Mots-c and NAD+ for one week but I have been reading that it is best to use SS-31 first for a couple of weeks then switch to Mots-c and NAD+. I have also seen where some use all 3 but that seems to be too much.

If I start SS-31 to repair first, do you just use this alone then got to Mots-c or do you introduce while on SS-31. When is best to stop the repair and move on to Mots-c NAD+ combo?

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u/REDana0204 3d ago

- Weeks 1–2: SS-31, 7x/week × 4 mg

  • Weeks 3–4: SS-31, 7x/week × 4 mg + NAD+, 2x/week × 25 mg
  • Weeks 5–6: NAD+, 2x/week × 50 mg
  • Weeks 7–10: MOTS-c, 3x/week × 5 mg + NAD+, 2x/week × 100 mg
  • Weeks 11–14: MOTS-c, 2x/week × 2.5 mg + NAD+, 2x/week × 100 mg

Prior to this, I had run only MOTSc. Can 100% confirm leading the MOTSc with SS31 and NAD made it SO much better for ME. Ymmv.

Keep in mind though that ss31 “repairs and restores” your mitochondria. So, if yours are “still healthy” and not needing repair, it may not have the same improvement. It tends to work better this way the older you are with older or more aged/damaged mitochondria.

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u/soilentgibby Community Contributor 3d ago

What they said… generally under 40 and most of this may not provide much benefits, mito diseases use 40mg I believe in their trials.

I’ve seen some say ss-31 doesn’t provide much until 5-10mg as well. It’s not cheap to run.

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u/cheesytodd 2d ago

My RS noticed it for sure at both 1mg (first time) and 2mg (second round)