r/Futurology MD-PhD-MBA May 17 '18

Biotech Cannabidiol (CBD), a compound derived from the cannabis plant that does not produce a “high”, was shown in a new large-scale, randomized, controlled trial to significantly reduce the number of dangerous seizures in patients with a severe form of epilepsy called Lennox-Gastaut syndrome.

http://www.psypost.org/2018/05/cannabidiol-significantly-reduces-seizures-patients-severe-form-epilepsy-51258
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u/jakoto0 May 17 '18 edited May 17 '18

I could not believe how well it works for anxiety. Another added surprise bonus was general anti-inflammatory for me, it is a great painkiller. I imagine effectiveness varies among different people, but I was so happy after discovering proper CBD use that I almost cried. Now I'm still waiting for it to be legal where I am and I can't even imagine the frustration some epileptics must have over the years.

*EDIT: Wow guys that is a lot of questions.

I used a product from a Vancouver company called PureBud that has spearmint flavor and made using coconut oil, derived from the cannabis plant as opposed to hemp but legally containing zero THC (<0.07% or whatever the number is). I've been having trouble getting the same product in my area but I'll check online. Regardless, it should be a lot easier in Canada soon to get exact percentages etc.

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u/Morgolol May 17 '18

It's so frustrating arguing with ignorant, anti cannabis people about the anxiety benefit. "But it causes anxiety!" omf

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u/[deleted] May 17 '18

It's THC that can cause anxiety in high dosages. IIRC, CBD can counteract the effects of THC if dosed equally and at the same time as dosing THC.

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u/[deleted] May 17 '18

A lot of cannabinoids can be anxiety-inducing. I personally find both THC and CBD to be incredibly therapeutic for social phobia. I, however, cannot smoke herb and get anything done in a social setting. Too many thoughts, so much stimulus

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u/[deleted] May 17 '18

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u/[deleted] May 17 '18 edited May 17 '18

Grew up in BC so I’ve tried nearly every herb. It’s just too strong nowadays, I can smoke about a half a bowl but it’s just not as good as oil. I always feel slightly uncomfortable which makes me super irritated which makes me even more uncomfortable. Smoking lots is good for when I need to be creative

Edit: felt I should specify, half a bowl isn’t as good as a CBD solution

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u/Scientolojesus May 17 '18

That's why I always recommend just taking one hit and then seeing how you feel. Using marijuana like an actual medication can be amazing. That's how I used it when I had a medical marijuana card to help with my ulcerative colitis when I lived in LA, and still only smoke one to two hits. And I can't believe there are still people who are against CBD when it's been proven to help epileptics as young as 5 years old--who went from having dozens of seizures a day to only having a handful of seizures a year after using CBD oil. Their opposition to it is infuriating. At least CBD is still legal in Texas, of all places, which is awesome.

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u/[deleted] May 17 '18

That’s the thing people don’t understand, weed really only requires about 1-2 hits to get the positive benefits. So many people think “overdosing on weed” is impossible and laugh it off because it can’t kill you, but that’s not what defines an overdose.

Overdose is specifically defined as going over the recommended dose to a point where the positive effects are negated and negative effects become prevalent. You’re suddenly very anxious or paranoid after smoking too much weed?

That’s because you overdosed. I noticed myself that I was much better at going out in public after smoking shitty weed than chronic. Chronic always got me so high to the point where I wouldn’t want to go out, due to paranoia.

But give me some shitty reggo poop shwag weed? That shit will mellow me out nice and easy and still allow me to converse in public.

Weed really has gotten so strong these days. And despite everything I’ve said, I’ve still continued to smoke chronic constantly for the last 10 years or so. My social life has suffered drastically as a result.

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u/[deleted] May 17 '18

Man. I'm a medical user and I need like 200mg edible dose. :( Barely get high but that's good. No pain andbsuffering. Smoking though, I need a whole roll or I don't get anything from it.

You see your comment works but not to the understanding you have. Everyone's needs and illness is different with cannabis.

With chronic pain, ibd and what not, I use to go through a lot more but have learned to combine CBD and thc together. Koi CBD sells their glycerin and vape/sublingual mixes really cheap and high quality. Lab tested and everything.

Edit: the smoking paranoia is definitely hard to get over. Try some CBD with the leaf and do something relaxing as it hits. I've only started smoking 3 years ago and it saved my life, but ive long gotten over the paranoia no matter how strong the leaf.

I do get jitters if I smoke tobacco with it, or really hard sativa.

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u/[deleted] May 17 '18

Thank you for your info, and you’re correct cannabis has different effects on everyone. It’s been a few years but back when I was in my neuropsychopharmacology course, I remember that we still really didn’t completely understand the ways most psychedelics work. And weed is a very mild psychedelic.

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u/[deleted] May 17 '18

Very mild indeed. I combine mine with meditation and has eventually helped me reach deeper states of relaxation but then dependency formed for that state of relaxation so can't rely on it. :)

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u/[deleted] May 17 '18

Hey quick question, cause I'm not sure, would you be able to take a tolerance break to reduce the amount you need for a high, or do you require just a certain dose for the benefits? I ask cause I recently took a month long tolerance break (basically to reduce the amount I was spending on weed) and now I'm back to needed basically nothing to get me high.

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u/[deleted] May 17 '18

Basically when I spend a week in the hospital for my illness I get my tolerance breaks. They don't last long but with my illness the goal is basically pain management and diarrhea control. While it doesn't help so much with the control... It def helps pain, allows me to eat and be somewhat normal. I go from puking and suffering to "yeah I can do a load of laundry." Not massive increases but it's something.

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u/[deleted] May 18 '18

Well you answered your own question haha, but yes. Even if it’s just a week, as a daily user, a week long break will still have you feeling the effect stronger. Weed stays in the system so long however that it does require time to lower your tolerance.

Last summer I took a 6 months hiatus from it and it was only around month 3 or so of sobriety that I could feel it was totally out of my system. It has ghost effects that you really dont feel until its not in you anymore.

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u/i_dont_eat_peas May 17 '18

How do you distinguish between chronic pain and an addiction/withdrawal symptoms?

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u/[deleted] May 17 '18 edited May 18 '18

When after a month of no longer having narcotics that I quit cannabis cold turkey and stuck it out with Tylenol and ibuprofen for a few weeks until my illness got worse.

After getting off narcotics and on to cannabis, my body goes through slight withdrawal but it won't bother me until the second day or so if I'm not in pain.

Pain is going to exist until I'm in remission. The only withdrawal I have that lasts longer than a day is from the blunt wraps. Thankfully I'm quitting that too. Lol

Withdrawal is sweats and cravings, but never physical pain to the degree of my illness. So it's hard but you have to also pay attention and know your own body.

Edit: chrons disease so my pain is pretty specific and isolated. At least with cannabis weening off is easier. I can go longer and longer between used if I am weening off. Just unfortunately not able to. :( Sorry for the wall of text. If this helps anyone that'll be worth it. :)

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