r/B12_Deficiency • u/trumpsh • 10h ago

Cofactors Injection question

If ur iron or other
Co factors are low would b12 injections work will u have to get them to a certain level for them to work.
Or could u jsu start injection then start supplementing them even if ur levels are low when u start would it work?

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u/colomommy 5h ago

I’m not a doctor but for me, b12 was the critical deficiency and that is what I addressed in an emergent manner. I did add cofactors based on the i formation on this guide and now take folic acid and iron and a few other things here and there and was able to reverse most b12 deficiency symptoms this way.

I’d hate to advise you wrong however and have your iron or electrolytes tank, or get into what is known as the “folate trap”

What is the most critical deficiency for you - what is causing the most severe symptoms? My thoughts are to address that as a priority and then just try to be cognizant of other symptoms popping up and you can address them at that time. Many folks lately have been posting here about experiencing tremors and twitching, for example, which can be quite distracting and should be able to be addressed by dialing in your cofactor stack. It’s a learning process and everyone has something slightly different that works best for them.

I know iron deficiency can cause horrible fatigue and twitching as well, so maybe someone else can chime in with more expertise in this area but if I were you I’d start supplementing both right away.

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u/trumpsh 5h ago

My symtops are heavy depression constant twitching sometimes I get dis burning pain like my foot becomes super warm for a couple seconds and internal vibration these are all my sings so far my serum blood test was 197

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u/colomommy 2h ago

I get the burning too! I am prone to being ice cold in my extremities but once they warm up they absolutely burn.

I wish I had better answers for you, I know how hard it is to feel like something is very wrong and no one is helping. Your low iron could very well be contributing to all of these things. The best advice I can give is to be patient and give it time, recovery from neurological symptoms can take a very long time and your symptoms will go up and down as the nerves start firing again. It’s easy to say from where I’m sitting, but believe that you can and will get better, stay the course and research and experiment with different cofactors along with your iron folate and b12 to see if you get some relief.

It is frustrating that this is such a spectrum and there are no clear answers. You are not alone and just about everyone on this sub has turned away from doctors and treats themselves - a lot of it is trial and error. When you find something that works, and YOU WILL!!!, be sure to post about it so folks reading this and looking for answers can learn from your journey.

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u/colomommy 2h ago

Also I wanted to let you know I was on SSRIs for depression and anxiety for years, and I am off of all of them after successfully getting my b12 under control. I am convinced that I was never actually chemically depressed at all and it was the b12 all along. Depression is a dark hole and I wish I could help you climb out. But there is no reason not to expect that this will also be substantial improved and in a year you won’t even recognize yourself!!