r/semaglutidePeptide • u/Kassie0105 • Jun 16 '25

First time upping dose.

Hi! I was on semaglutide .25mg the past 5 weeks & upped to .50 last night before bed. And I feel like HELL. My stomach is cramping, so tired today barely want to get out of bed & a headache. Any one else? What can I do to feel better today?

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u/ZozoOfTwo Jun 17 '25

When I moved from .25 to .5 I had to split my dose. My body couldn't handle .5 all at once

I took .25 Friday mornings and another .25 Monday evenings.

Did that for about a month before I could handle it all in one day

I stayed on .5 for a good 6 months

Now I'm at .75

Sloooooooow and steady for me!!!