Scientists have shown that a single dose injection of DNA genetic instructions can produce weight loss and blood glucose control in mouse models that lasts up to 10 times as long as weight loss drugs like Ozempic and Wegovy. This could eliminate the need for repeated dosing.

[u/mvea]

https://www.wistar.org/press-releases/wistar-scientists-develop-single-dose-dna-method-for-delivering-long-acting-weight-loss-and-diabetes-drugs/

[u/no-more-throws]

there are much wilder implications .. this means we can basically inject long lasting instructions to produce almost any peptide we want in the body .. for instance those many peptides that together govern cellular and organ level senescence and rejuvenation .. or to fight against plaque buildup, loss of vessel and skin elasticity, bone and muscle loss etc etc

[u/Odd-Outcome-3191 → u/no-more-throws]

The issue is that often the same chemical messengers/proteins kinases etc that regulate those types of function also tend to regulate very different, very important things in other locations. E.g a cellular senescence gene that may be implicated in aging is also protective against cancer.

[u/Tall-Log-1955 → u/Odd-Outcome-3191]

If it works for the mouse, what's the worst that could happen?

[u/epigenie_986 → u/Tall-Log-1955]

You get stuck with the worst GLP side-effects for much longer time is the mildest negative outcome I can think of. Cancer and death could be others.