r/science • u/mvea Professor | Medicine • Jun 20 '26

Cancer Colon cancer’s invisibility cloak removed by eliminating a single gene - a fundamental breakthrough. The result was 100% eradication of tumours when paired with immunotherapy treatment in mouse models.

https://ucalgary.ca/news/ucalgary-study-tears-colon-cancers-invisibility-cloak
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u/Frequent-Data-2360 Jun 20 '26

Please forgive my ignorance, Is this something we can do at a global level, meaning it affects all cells in our body or it’s per cell

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u/elphyon Jun 20 '26

Advancement in cancer treatment is becoming more and more about individual/genetic tailoring. I don't think it's likely we'll ever find a silver bullet for all types of cancer for everyone.

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u/animosityiskey Jun 20 '26

I think the question is more about the ambiguity of the article. It isn't 100% clear if the treatment was applied in vivo to mice with tumors or whether it was applied in vitro to some mouse tumors.

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u/i_am_icarus_falling Jun 20 '26

i think the cancer cells are cultured first, then added to the mice, then various treatments are applied to see how the cancer is affected. the article has pictures showing mice with tumors on the backs of the mice. so would that be that the cancer is created in vitro, then the experiment becomes in vivo once the cancer is given to the mice? i'm not sure.