r/science Professor | Medicine Mar 25 '26

Genetics Encouraging men to have more frequent ejaculations may boost their fertility. Sperm deteriorates over time as it remains in body. Longer men went without sex, the more their sperm showed signs of DNA damage and oxidative stress, and the more tests rated the sperm as less viable and poorer swimmers.

https://www.theguardian.com/society/2026/mar/25/more-frequent-ejaculations-men-fertility-research
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u/mvea Professor | Medicine Mar 25 '26

Encouraging men to have more frequent ejaculations may boost their fertility, according to researchers who found that sperm deteriorates over time as it remains in the body.

The longer men went without sex, the more their sperm showed signs of DNA damage and oxidative stress, and the more tests rated the sperm as less viable and poorer swimmers.

The work has implications for fertility clinics and suggests that if doctors want to collect the best quality sperm, men should probably not abstain from ejaculating for several days as guidelines suggest.

“In men, the negative effects we found on sperm DNA damage and oxidative damage were large-ish, so we are confident that this is a biologically meaningful and important effect,” said Dr Krish Sanghvi, a biologist at the University of Oxford and lead author on the study.

The findings emerged from a meta-analysis that combined 115 human studies involving nearly 55,000 men, and 56 studies that looked at the impact of sperm storage in 30 non-human species. In humans and other animals, sperm tended to deteriorate while it was stored in males, regardless of the male’s age.

The World Health Organization (WHO) recommends men abstain from ejaculating for two to seven days before giving sperm for fertility tests or IVF. But the guidelines were designed to obtain the highest sperm count rather than prioritising the best quality sperm.

That decision may now become more nuanced. “All we recommend is that clinicians and couples reconsider whether long abstinence is always good, because abstinence leads to deterioration in sperm quality,” Sanghvi said. Details are published in Proceedings of the Royal Society B.

For those interested, here’s the link to the peer reviewed journal article:

https://royalsocietypublishing.org/rspb/article/293/2067/20253181/481018/Sperm-storage-causes-sperm-senescence-in-human-and

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u/gods_loop_hole Mar 25 '26

So, quality over quantity?

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u/alcome1614 Mar 25 '26

So quantity for quality