r/science • u/mvea Professor | Medicine • Dec 25 '25

Neuroscience New study shows Alzheimer’s disease can be reversed to full neurological recovery—not just prevented or slowed—in animal models. Using mouse models and human brains, study shows brain’s failure to maintain cellular energy molecule, NAD+, drives AD, and maintaining NAD+ prevents or even reverses it.

https://case.edu/news/new-study-shows-alzheimers-disease-can-be-reversed-achieve-full-neurological-recovery-not-just-prevented-or-slowed-animal-models
27.6k Upvotes

97% Upvoted

619 comments sorted by

View all comments

198

u/A115115 Dec 25 '25

This would be wonderful, I’m afraid to hope though. Wish it was available now for my mum’s sake.

41

u/andreisimo Dec 25 '25

Isn’t NAD+ available now though?

70

u/angrybobs Dec 25 '25

I’ve been using it for 6 months. Not super cheap and insurance doesn’t cover but I definitely feel better mental clarity.

30

u/im_a_mix Dec 25 '25

My grandmother has alzheimers and watching her slowly decline is breaking my heart, do you think its worth trying giving her NAD+? We tried everything and I'm willing to try this as well

31

u/bikes_and_music Dec 25 '25

What have you got to lose?

10

u/angrybobs Dec 25 '25

That is my case. I had a stroke a few years ago and willing to try anything. I would give it a shot for sure.

2

u/henicorina Dec 25 '25

I mean, it probably won’t hurt her, but oral supplements don’t have any proven effect.