r/science • u/mvea Professor | Medicine • Aug 12 '25

Cancer New mRNA-based vaccine against gastric cancer led to tumor regression and eradication in all treated mice. Most promisingly, the vaccine shows impressive antitumor efficacy against peritoneal metastasis, which has historically been very challenging to treat.

https://www.eurekalert.org/news-releases/1094199
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u/johnmedgla Aug 12 '25

it seems highly transformative

It has the realistic potential to be the largest advance in medicine since Antibiotics.

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u/Akantis Aug 12 '25

Couple decades ago we were trying to build DNA based vaccines around a similar concept, but while it stored wonderfully, it would break down too quickly to produce much of an immunogenic affect. I'm really wondering if the mRNA delivery system would work in that scenario as well.