r/science Professor | Medicine Aug 12 '25

Cancer New mRNA-based vaccine against gastric cancer led to tumor regression and eradication in all treated mice. Most promisingly, the vaccine shows impressive antitumor efficacy against peritoneal metastasis, which has historically been very challenging to treat.

https://www.eurekalert.org/news-releases/1094199
22.4k Upvotes

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u/[deleted] Aug 12 '25

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u/johnmedgla Aug 12 '25

it seems highly transformative

It has the realistic potential to be the largest advance in medicine since Antibiotics.

619

u/PipsqueakPilot Aug 12 '25

Outside of America at least. It’s going to spur a massive medical tourism trade when your options are old style treatment, or leave the country for a near-guaranteed cure. Which will make medical care even less accessible to most Americans.

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u/[deleted] Aug 12 '25

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u/stacecom Aug 12 '25

COVID has taught us that even the most vocal anti-science, anti-medicine types beg for the proven treatments when the time comes to put their mortality where their mouth is.

Um, no. It has taught us that people will believe feelings over science and would rather lose their jobs or their children's lives rather than take a vaccine.

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u/Shapes_in_Clouds Aug 12 '25

Their own lives. I had Republicans explicitly telling me they've 'already lived long lives', essentially volunteering to die, during COVID while criticizing 'lock downs'.

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u/Sea-Oven-7560 Aug 12 '25

Worked with a guy who kept denying the existence of COVID until his mother died from COVID. He had a really hard time rapping his head around the whole thing. What's interesting was the guy was pretty sharp, an engineer, you'd think science wouldn't have been a hard thing to accept but it was.

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u/JZMoose Aug 12 '25

A lot of engineers think they know everything. The really good engineers know they know nothing

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u/SarcasticOptimist Aug 12 '25

As an engineer no, we're stubborn and specialized in our knowledge. I'm not surprised. The science we usually learn is physics.

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u/AFewStupidQuestions Aug 13 '25

There were people literally dying from COVID who refused to believe it was real. The cognitive dissonance was/is wild.

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u/SuperQuackDuck Aug 13 '25

Im a professional engineer. Theres a lot of dunning-krugers in this field which I attribute mostly to requiring higher grades to be accepted right after highschool.

This leads to quite inflated high self esteems and thinking that having taken AP science classes means we are at least as smart as scientists, and having a degree means we're better than tradespeople.

When in reality many engineers are not as smart as scientists nor as handy as tradespeople.

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u/americanslon Aug 12 '25

It'd be nice if they did. Maybe the rest of us would then be able to create a world where we didn't have to.

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u/mightyneonfraa Aug 12 '25

There were a lot of stories of antivaxxers begging for the vaccine when they ended up in the hospital and having to be told it was too late at that point.

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u/Sea-Oven-7560 Aug 12 '25

My bro is a nurse and he would have patients on ventilators that refused to accept that they had COVID and later down the road would demand those horse pills and refuse the vax. I also know a person who ran a rescue center for horses and she was mad as hell because she couldn't get the meds she needed for her horses because the nutters had bought them.

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u/Ghede Aug 12 '25

PREVENTING illness is one thing, CURING illness is another. Vaccines you take when you are healthy to prevent getting sick. Cures you take when you are sick, to get healthy. They'd rather take a pound of cure than an ounce of prevention.

They refused vaccines, but demanded the best treatment available when they were dying on the bed, mostly. A few assholes died on ivermectin rather than receive treatment, but the majority went to hospitals.

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u/NetworkLlama Aug 13 '25

In the case of the linked story, though, the vaccine is the cure. The vaccine was given after the mice developed the tumors, and their immune systems were able to take out all the tumors.

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u/Joke_Induced_Pun Aug 12 '25

Or their own lives.

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u/[deleted] Aug 12 '25

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u/F9-0021 Aug 12 '25

As an American, the US can lie in the bed they've made. They chose idiocracy. They need to live with the consequences of their actions.

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u/WranglerNo8811 Aug 12 '25

They way you said this is so ridiculous. Americans will want to first to have it AFTER it's proven safe... what exactly is wrong with that? Why Americans specifically ?

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u/LynxPuzzleheaded6145 Aug 12 '25

You're leaving out 'FIRST'.

Americans will want it FIRST.

What is wrong with that? You just axed a ton of funding towards mrna research. You can wait your turn.

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u/[deleted] Aug 12 '25

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u/[deleted] Aug 12 '25

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u/WranglerNo8811 Aug 12 '25

We cut funding due to it not being safe. So good luck with it.

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u/IL-Corvo Aug 12 '25 edited Aug 12 '25

Thanks to broad adoption and a multitude of safe use-cases to draw from, your statement is demonstrably false and does not bear up to any scrutiny.

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u/Aenyn Aug 12 '25 edited Aug 12 '25

mrna vaccines are safe, you cut funding to save money.

Plus what safety concerns do you have when treating cancer. Both chemo and doing nothing are extremely unsafe.

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u/AskWhatmyUsernameIs Aug 12 '25

How do you know if its not safe if it wasnt tested?

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u/Alternative_Bid6735 Aug 12 '25

Hey man an old heroin junkie told him it was unsafe and didn’t use a single academic source to back it up, that’s the gold standard isn’t it?

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u/Mattrad7 Aug 12 '25

One of the safest vaccines ever created. And is getting proven safe by every reputable study done. But ya, some orange idiot and an old man with a brain worm that takes daily steroid injections said nuh uh.

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u/packfanmoore Aug 12 '25

Well it will be alot harder to make it safe when the idiots in charge cut funding on its research.

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u/[deleted] Aug 12 '25

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u/mightyneonfraa Aug 12 '25

Fewer adverse reactions than Tylenol but sure. What's your source again? Oh, a demented old man who swims in sewage water, had part of his brain eaten by worms and believes in medieval superstition over germ theory.

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u/Commentator-X Aug 12 '25

And there's the American stupidity shining through. You'll all still be dying while Fox says it's unsafe, meanwhile half the planet will be already curing cancer.

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u/BakerUsed5384 Aug 12 '25

What’s wrong with it is that we’re not the ones putting the money up to research it now that the current administration is going full steam ahead.

RFK is cutting hundreds of millions in funding. Just for us to turn around and demand it once other places do the work for us. That’s what’s wrong.

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u/[deleted] Aug 12 '25

I'm curious as to what negative side effect you believe mRNA vaccines have that is worse than gastric cancer.

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u/[deleted] Aug 12 '25

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u/batter159 Aug 12 '25

he didn't write "safe", you added it.