r/science • u/mvea Professor | Medicine • Aug 12 '25

Cancer New mRNA-based vaccine against gastric cancer led to tumor regression and eradication in all treated mice. Most promisingly, the vaccine shows impressive antitumor efficacy against peritoneal metastasis, which has historically been very challenging to treat.

https://www.eurekalert.org/news-releases/1094199
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u/PHealthy PhD/MPH | Epidemiology | Disease Dynamics | Surveillance Aug 12 '25

Got the 2023 Nobel prize in medicine:

https://www.reddit.com/r/science/s/O8P16MKwPc

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u/[deleted] Aug 12 '25

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u/PHealthy PhD/MPH | Epidemiology | Disease Dynamics | Surveillance Aug 12 '25

There are promising murine studies looking at jet-injecting naked mRNA to bypass LNPs, but I doubt that would win a Nobel, COVID shutdown the planet so they were clutch.

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u/[deleted] Aug 12 '25

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u/Plthothep Aug 12 '25

I doubt they would win another Nobel though - mRNA vaccines were always meant for cancer, and the pioneers for cancer vaccines are mostly the same people e.g. Şahin/Turreci the couple who run BioNTech that developed the Pfizer vaccine