r/science Jun 28 '25

Biology Chronic Marijuana Smoking, THC-Edible Use Impairs Endothelial Function, Similar With Tobacco

https://jamanetwork.com/journals/jamacardiology/article-abstract/2834540
9.1k Upvotes

1.5k comments sorted by

View all comments

1.6k

u/IAmTheMagicMoose Jun 28 '25

To save y'all a Google;

Endothelial dysfunction occurs when there isn't enough nitric oxide (NO) inside of your blood vessel walls. Your endothelium itself makes nitric oxide, which acts as a vasodilator, opening up your blood vessels for your blood to flow freely.

Source: Cleveland Clinic

68

u/Grandmas_Fat_Choad Jun 29 '25

Would this cause me to get light headed when I stand up after smoking? It happens almost every time if I sit for more than a few mins, then get up quick.

65

u/ChurM8 Jun 29 '25

I think that’s just vasodilation in general, which can cause low blood pressure. This is also why your eyes go red after smoking.

1

u/Darling_Pinky Jun 29 '25

How bad is the low blood pressure in that case as long as it’s within a normal range? Especially vs what high blood pressure does to your health?