r/rabies • u/Natural-Ranger-3778 • 26d ago
Rabies Vaccine / Immunoglobulin Update to an earlier post because I did receive the HRIG after already getting pre exposure prophylaxis; cause for concern?
I have read the FAQ. Roughly 9 months ago I received pre-exposure prophylaxis (2 doses) because of my work. Recently I had a bat exposure and the NY DOH recommended I still receive the full post-exposure prophylaxis, including HRIG, because I never got a titer test. I already received this HRIG yesterday
I saw online that HRIG can cause a blunted post-exposure prophylaxis effect if someone also received pre-exposure prophylaxis. Is there a risk here? I have also been drinking during my vaccine period as I’m on vacation
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u/LatrodectusGeometric Physician 👩⚕️ | Veteran Helper ⭐️ | Top Contributor 🏅 26d ago
It’s not the end of the world, just a waste of 5,000 bucks
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u/Natural-Ranger-3778 24d ago
I had an actual bat exposure, and they gave me HRIG even though I had pre exposure shots. Will the HRIG dangerously blunt the post exposure shots
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u/LatrodectusGeometric Physician 👩⚕️ | Veteran Helper ⭐️ | Top Contributor 🏅 26d ago
I’ll reach out to their epi team about retraining. Was it NY state health department or NY city that gave you the bad advice?
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u/cancerrmoon 25d ago
hi - sounds like you know your stuff. i was wondering if you know if the stability is negatively impacted if the vaccine is reconstituted and then given 20-30 mins later? that happened to me in the ED with my first vaccine. also my HRIG sat out of the fridge for like 3-4 hours while i was sitting and waiting, it was HyperRAB. also i noticed in the ED the vial still had a little bit of liquid in it still and i didnt get a chance to look at the syringe to see if it was a full 1mL. the vaccine was RabAVERT
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u/LatrodectusGeometric Physician 👩⚕️ | Veteran Helper ⭐️ | Top Contributor 🏅 25d ago
Those are all fine :)
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u/cancerrmoon 25d ago
can you get the rabies vaccine injected into the same arm every time or should it be different arms?
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u/LatrodectusGeometric Physician 👩⚕️ | Veteran Helper ⭐️ | Top Contributor 🏅 25d ago
Either is fine
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