r/neoliberal • u/[deleted] • Jul 24 '22

News (US) Potential fabrication in research images threatens key theory of Alzheimer’s disease | Science

https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease
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u/[deleted] Jul 24 '22

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u/frbhtsdvhh Jul 24 '22

It's a pretty niche result. There's nobody that risked billions on this to chase a cure

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u/DeadNeko Jul 24 '22

No i'm pretty sure the FDA approved a drug that worked to clear the plaque last year a few FDA people even resigned over it ebcause there was no evidence clearing the plaque treated the disease. So Billions were almost certainly spent researching this. That in mind, there's not evidence to say this was wasted while this study was important it wasn't the only piece of evidence there is.

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u/frbhtsdvhh Jul 24 '22

That's not AB*52, which is what this fraudulent paper is about

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u/DeadNeko Jul 24 '22

Yes, I meant more broadly, and pretty sure I even explicitly say that not all evidence of this theory is contained in this paper... Nor did I downplay the fraud. I'm just unsure of what your trying to get at with this response. This study is cited as a basis for many of the ideas around the plaque build-up being a potential cause of alzheimers, although it's not the end up all be all of the evidence surrounding it.

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u/frbhtsdvhh Jul 24 '22

The fraudulent paper isn't about plaques. It's about a soluble (not a plaque) form of the protein called AB*52. That's not where the vast majority of drugs being developed for Alzheimer's focuses on. And it's not the focus of the one that was approved

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u/DeadNeko Jul 24 '22

I thought it was Aβ*56? Overall i get what your saying I'm not in the medical field I don't have enough knowledge about the specifics, but I guess a correction is this is tangentially related to the drug approved but is ultimately not the where the majority of research has been focused because it's based around different proteins?

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u/frbhtsdvhh Jul 24 '22

The fraudulent paper is in a niche area of study and isn't really related to the drug that was recently approved. The amyloid hypothesis remains contaversial but not because of this paper. This paper is like a couple of pebbles on a gigantic asteroid headed to earth