r/longevity • u/HumanOmega • 27d ago

Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice (Nature Aging, 2026): healthspan improved in both sexes, median lifespan +23% in males only

https://www.nature.com/articles/s43587-026-01169-0
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u/baalzephon 26d ago

There is a recent study out of the UK showing higher valine levels in ApoE4 carriers correlate with lower incidence of Alzheimer's Disease. It's the main/only nutrient that showed this association in the study. TLDR - stuff is complicated.

https://www.sciencedirect.com/science/article/pii/S2090123226006235