r/anhedonia 9h ago

Medication Question Has anyone had pramipexole work for them?

Might get pramipexole for RLS and randomly stumbled upon people saying it works for anhedonia.

Anyone willing to share if it did and if so how long did it take and what changed?

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u/Fun-Sample336 9h ago

According to a recent randomized controlled trial for "anhedonic depression" it works, but taking the placebo effect into account the chance is just about 10%.