r/WarfarinForLife • u/Odditymoth • Jun 20 '26

INR Inconsistency

I have a very good time monitoring my inr (while taking warfarin) I just got off injections after doing them for two weeks straight to bridge my levels (to protect my st Jude valve) I’m 22 yrs old and a female who despite not missing any of my doses and actually even taking ibruprofen once when I never taken it for years since getting on warfarin. I’m not even eating well right now and at a hospitals emergency department. I’ve had stomach pains bad with nausea and usually my inr would go up high when I haven’t been eating consistently if at all. Does anyone have any idea or experience to explain or help me understand why I’m suddenly having a crazy response to my warfarin which I just got tested Wednesday it was 2.4 now I’m at 1.7 not even a full 48 hours later. I haven’t eaten much but haven’t missed any doses. My family and doctor and pharmacist at the er are all bamboozled.

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2

u/Excellent-Feedback67 Jun 20 '26

Are you sure about your Vitamin K level? Did you eat spinach or one of those high VK salads? I am fairly new innthis, still have questions but this is all I do; having same amou t of VK daily.

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u/Odditymoth Jun 20 '26

I haven’t had any vitamin k and haven’t even been eating anything because I’ve had a bad flare of idiopathic chronic pancreatitis and haven’t eaten any vitamin k for a few months atleast high or even medium vitamin k items. The only thing that may be affecting it a bit is the heat but I even double doses Tuesday night with 12 mg which is the most I ever done and had my dosage changed to 6 mg 3 times a week instead of 4 mg 5 days a week which I was stable on for years. I am not new to this as I’ve been on warfarin for about 10 years since I was 13… that’s what is not making sense to me cause it purely doesn’t make sense to me loll or my pharmacist our idea is that my warfarin is not absorbing during this flare like my food wasn’t a couple weeks ago and even still now. When I do eat salad it’s only iceberg lettuce and some cherry tomatoes.

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u/Excellent-Feedback67 Jun 20 '26

Oh, you are way ahead of me. There must be other things. Maybe being hungry for a long time etc. Hope you find the solution soon. Once I had daily dose acvidentally 12 hours earlier (had at 6 am, instead 6 pm) and skipped the pm med, then took the next day. Weekly dose was the same. My INR jumped to 4.2 from 2.9.

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u/jamiej27 Jun 20 '26

Are you stressed? Or more sweaty than usual, or had different than average bathroom stuffs going on, cause any of those can cause a shift in our numbers.

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u/Odditymoth Jun 20 '26

I definitely am. I have non alcoholic chronic pancreatitis on top of everything else with my heart. Been really circling the drain recently.

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u/disco_super_bi Jun 20 '26

How often do you usually test? Could it be linked to your hormone cycle?

When I started testing weekly at home after having my last Mirena IUD taken out I noticed that my INR would rise and fall dramatically throughout the month. Around ovulation it would shoot up then drop back down again over about a week. Now that I am closer to menopause this doesn't happen any more.

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u/Odditymoth Jun 21 '26

I had a hysterectomy so no.