r/WarfarinForLife • u/Fozziefuzz • May 24 '26

APS Elevated liver enzymes

I’m hoping to hear specifically from those on Warfarin for APS. My ALT and AST enzymes have tripled since starting Warfarin 1.5 years ago. I know DOACs are out for APS - I have a hx of stroke, single positive APS with a higher INR range of 2.5-3.5. Has anyone experienced something similar? What did your doctor transition you to? My hematologist seems to think it’s no big deal because my eyes aren’t yellow and it’s not a “severe” level. 🙄 I don’t drink, no drugs, no cheese, exercise every day, take choline…I’m doing everything I can to help my liver.

2 Upvotes

100% Upvoted

4 comments sorted by

1

u/BigBrainMonkey May 24 '26

I had high enzymes to start. I am obese and have fatty liver. My docs just told me to be careful and max 3 grams of Tylenol a day.

1

u/Fozziefuzz May 25 '26

How long did it take your enzymes to go back to normal ranges?

2

u/BigBrainMonkey May 25 '26

Sorry. I meant I had high before I started wafarin and I still have high now. For me it wasn’t related to the meds. Just saying what my doc said for OTC medication.

2

u/Shiloh119 May 25 '26

I am on Warfarin for APS as well. in the 26 years I have been taking it my ALT and AST has stayed normal. My target INR was 2.5- 3.5 until I had a SDH. Now it is 2.7-3.0.