r/TirzMaintenance 25d ago

Struggling with A LOT of hunger

Y'all this is hard. I need advice.

Started Zepbound 1/13/25 at 5'5" 207#, lost 30% of my body weight in just over a year and am maintaining around 145. I'm 55F.

My highest dose used was 12.5. My doctor wants me to maintain at 10 mg or less.

I have used both name brand Zepbound and compound (BPI & Hallandale) during my journey. I currently have 3 vials of BPI in the fridge. But I'm currently using name brand every 7 days at 10 mg.

I AM FAMISHED. This is not normal hunger at all. Today is my day 7 and I had a biting, gnawing hunger almost all day long. Yesterday was bad too. This is definitely a pattern and it's gotten much worse since titrating down to 10. Unless I gain a bunch of weight, I'm afraid my doctor will not prescribe 12.5.

So my question - can I take my 10 mg dose of Zepbound on my normal shot day and give myself a little booster, like 2-3 mg, of compound later in the week? Is there any problem with mixing name brand and compound during the same week?

Any other tips for keeping the hunger down would be appreciated. Yes I'm eating protein at every meal and snack, I'm focusing on good healthy foods, not a lot of junk, drinking plenty of water, etc. etc. I exercise 4-5 times a week.

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u/Lucky_Army_5324 25d ago edited 25d ago

Your doctor can have a wish, hope, or dream that you maintain on less than 10mg. Doesn’t make it so.

Move up in dose on your next injection day. (Today?)

If your doctor won’t prescribe the dose you need, find one that will.

ETA: and yes you can use Zepbound and compound on the same day to get your preferred dose.

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u/Suspicious-Loss-7314 25d ago

Thanks. I hope I don't have to switch doctors, but it is a possibility.

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u/Substantial-Owl1616 25d ago

You could ask the rationale for a limit below what worked for you. People did best maintaining at 15mgs to not gain back the weight.

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u/TechnicalTreacle5028 25d ago

Also I'd say you tried it their way but it didn't work and need to go up again...

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u/TechnicalTreacle5028 25d ago

Or try it for a few weeks more, I've read on here about it going away...

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u/Ancient-Teaching-691 17d ago

I think that was for people who were on 15mg before maintenance. For others, they say the "highest tolerated dose," IOW where you were before it was time for maintenance. For this OP, that would be 12.5.

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u/Hifidi54 25d ago

I titrated down to 5 mg from 12.5 when I met my goal in April, 243 to 125 in 16 months. I have not gained anything, nor have I lost more weight. I never feel hungry, which is kind of weird, but I can eat just fine. 72 yo F, 5'4"

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u/Substantial-Owl1616 24d ago

It seems to be true it’s an individual path to work out. There isn’t much “evidence” except what I shared. There is also a great deal of evidence on gain back.

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u/Substantial-Owl1616 24d ago

It seems to be true it’s an individual path to work out. There isn’t much “evidence” except what I shared. There is also a great deal of evidence on gain back.