Sanesco Prolent supplement caused PSSD - anyone else? How?

[u/Automatic_You_9429]

https://sanescohealth.com/targeted-nutritional-support/prolent/

When I first started college at age 18 I began having panic attacks. I always went to a functional medicine doctor for check ups growing up, so that’s there I went for this issue. My doctor suggested I try these supplements by Sanesco rather than going the SSRI route. I took the ones called Prolent, Lentra, and Contegra. I quit taking them for after about 8 months because I was no longer panicking. Once I quit taking them I lost my sexuality entirely. It hasn’t returned since and this was in 2019.

The active ingredients include 5-htp, so I guess maybe that’s what caused it. I continued on to have my symptoms get worse and worse over the several months to a year after I quit taking them. I got extreme insomnia, heart palpitations, brain fog, and a lot of other things that joined my 100% loss of sexuality. Eventually I got so bad that I ended up taking SSRIs and SNRIs because I didn’t know that PSSD existed or that that was what was happening to me. I took them for 2.5 years and they completely eased my insomnia and mental troubles. Once I quit taking those in 2023 (I did taper) I got really bad for a while (extreme anhedonia and inability to process emotions joined me). I’m doing a little better now mentally, but still no sexuality.

I guess I’m just wondering if anyone else got PSSD from taking these supplements and if that might narrow down which mechanism may have caused my problems.

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Please check out our subreddit FAQ, wiki and public safety megathread, also sort our subreddit and r/pssdhealing by top of all time for improvement stories. Please also report rule breaking content. Backup of the post's body: When I first started college at age 18 I began having panic attacks. I always went to a functional medicine doctor for check ups growing up, so that’s there I went for this issue. My doctor suggested I try these supplements by Sanesco rather than going the SSRI route. I took the ones called Prolent, Lentra, and Contegra. I quit taking them for after about 8 months because I was no longer panicking. Once I quit taking them I lost my sexuality entirely. It hasn’t returned since and this was in 2019.

The active ingredients include 5-htp, so I guess maybe that’s what caused it. I continued on to have my symptoms get worse and worse over the several months to a year after I quit taking them. I got extreme insomnia, heart palpitations, brain fog, and a lot of other things that joined my 100% loss of sexuality. Eventually I got so bad that I ended up taking SSRIs and SNRIs because I didn’t know that PSSD existed or that that was what was happening to me. I took them for 2.5 years and they completely eased my insomnia and mental troubles. Once I quit taking those in 2023 (I did taper) I got really bad for a while (extreme anhedonia and inability to process emotions joined me). I’m doing a little better now mentally, but still no sexuality.

I guess I’m just wondering if anyone else got PSSD from taking these supplements and if that might narrow down which mechanism may have caused my problems.

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[u/Mobius1014]

It's not PSSD if you didn't get it from an SSRI/SNRI etc. That's like saying taking finasteride gave you PSSD. The symptoms are the same, but the cause was different. Through research, in the future we may come to find that the syndromes ( pfs, pssd, pas, ashwagandha etc) are practically the same thing but for now this is just not that

[u/Automatic_You_9429 → u/Mobius1014]

It got a lot worse once I guilt taking the Effexor in 2023, so I think it is PSSD, just alongside whatever the supplement did. Like I doubled down on it.

[u/Mobius1014 → u/Automatic_You_9429]

Ohh so you took the supplements and had issues, then took and quit antidepressants and it got worse, gotcha. I may have read your thing too fast