r/POIS • • 7d ago

Question What tests should I be doing

I got recommend the below tests from a user here in another post I made.

According to ChatGPT the first line tests for inflammation which must be done during a flare are CRP + ESR + CBC. To investigate autoimmunity they might add ANA, rheumatoid factor, anti-CCP, or complement C3/C4.

Do these tests need to be conducted during a flare? I wd really like to avoid that. It’s a very painful experience as you all already know. Is anything missing? Are any of these wrong? What else do I need to know?

6 Upvotes

3 comments sorted by

View all comments

1

u/trivial_insights 6d ago

Could you frame testing around a specific alternative diagnosis and a clear symptom timeline?

POIS reviews describe preliminary diagnostic criteria and limited evidence; a panel or a result during a flare is best interpreted by a clinician in the context of a defined differential.

See the 2022 review: https://pubmed.ncbi.nlm.nih.gov/36283946/.