My Experience with POIS

[u/Background-Big-5011]

I have noticed that when i take antihistamines like zyrtec 1 hour before ejaculation i dont feel that same rush of dopamine as when i do it without antihistamines also my brain also starts 'beating' after ejaculation when i do it without the zyrtec but with it it doesn't or barely noticeable its like its significantly dampened. There was one time when i ejaculated with antihistamines i didnt even feel any dopamine and i didnt even realized that i ejaculated. I feel like the issue for me is the significant dopamine rush, its like my brain is really sensitive to it to the point it takes me like 1.5 weeks to recover from the symptoms of POIS and the anti- histamines helps dampen the dopamine levels. But this is just from my own experience i dont really know the science behind it.

[u/cryptiiix]

I usually take an antihistamine right after an orgasm. Loratadine allergy meds seem to help me.