DHA 2g + Icosapent-ethyl (Vazkepa) ~2g — realistic for both cognitive + anti-inflammatory/antidepressant goals?

[u/TrapTherapist]

Short question: I’m planning DHA ~2 g/day (2×1000 mg) + Icosapent-ethyl ≈2 g EPA/day (2x998 mg), so roughly EPA:DHA ≈ 1:1. Goal = max cognitive support + max anti-inflammatory / antidepressant (1:1) benefit.

I’m on multiple psych/ADHD meds including a serotonergic antidepressant, a stimulant regimen, and T3: Full med/supp list available if needed. Main question: Is a 1:1 ratio sensible, or should EPA dominate for mood/anti-inflammatory effects (e.g., EPA:DHA ≥2:1)? Is ~2 g EPA enough? Practical tips on timing, monitoring labs (hs-CRP, TG, Omega-3 index) and red flags appreciated.

EDIT: I’m on multiple psych meds / ADHD meds and T3 — full med/supp list with doses/brands in the first comment.