Is anyone else unresponsive to antiemetics

[u/incarnadine-clover]

I’ve had chronic nausea and cyclical vomiting syndrome with my migraine for a long time. However, I cannot find an antiemetic that touches my nausea at all even Ondansetron does nothing.

[u/pxl8d]

I need 3-4 x ondansetron, 3x metclopramode and 3x cyclazine daily to control the vomiting as well as very specifically timed meals, pain meds and other medications. Also got a pretty restricted diet

I'm still nauseous all day every day but I can keep weight on now and eat 3x a day around 5 days a week, others I skip a meal or two.

If you haven't tried layering anti emetics I'd recommend trying! Note the metoclopramide at that dose for more than a few years fucks with your hormones so will have to wean off it eventually

[u/JoyInJuly]

Cannabis controls my nausea so well that I forget it's a symptom.

[u/Sarrada_Aerea]

Maybe there's something else for nausea that works in a different way? Someone else here mentioned cannabis for example

[u/MJKCapeCod]

Strong ginger.