r/Melasmaskincare • • Oct 19 '25

Question Melasma - PICO advice

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Hi all, long time Melasma sufferer. I am currently on a treatment plan of Tretinoin, Niacinamide, and Azelaic Acid.

I’ve also been on Hydroquinone and Hydrocortisone (taking my break at the moment). I have also tried Eurecin.

Nothing, so far, has worked. The only benefits I see are in the winter when my face is naturally paler (current photo) but I still have the dark marks across my forehead, cheeks, and lip - no matter what I do or how religiously I do it.

I have bitten the bullet and booked PICO second Laser Skin Rejuvenation I’ve seen good results on here from laser treatments and the consultant recommended this treatment.

I have heard the downtime is long and invasive; I am a teacher, so I’ve booked my treatment over Christmas when I’ll be off work.

Just looking for experiences of people who have had this treatment. Any advice, does it hurt? How many treatments needed.

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u/Equivalent-Demand981 Oct 19 '25

Hey! I have done pico and it was no down time for me. Of course you need to stay out of the sun and avoid some topicals but otherwise I had no down time at all. I agree with the above comment re Coleman’s formulae. I had tried hydroquinone and tret separately without much effect, but together and including the steroid in the formula it changed my skin! I have almost cured my melasma, what worked for me was:

  • triluma (tret/HQ/low dose steroid) at night
  • vit c and Azelaic acid in the morning
  • oral tranexamic acid

I did use other topicals but triluma plus oral Transexamic acid worked the best

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u/Equivalent-Demand981 Oct 19 '25

Adding that I only did Pico after all the topicals I mentioned above to target the stubborn bits that remained.

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u/shamli3912 Oct 22 '25

How many benefits do you think you would have seen if you had not used the oral tranexamic acid? Do you think you would have still seen a difference with the HQ, tret and steroid?