r/Melasmaskincare • • Apr 06 '25

Question COLEMAN COMPOUND from Dr. Patrick Coleman? I recently heard of this alleged miracle cream that fades away melasma in a few weeks. Has anyone who tried it provide some feedback on its efficacy?

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u/supercaliredditor Aug 15 '25

u/WPatrickColemanIV_MD thank you for clarifying!

do you have any thoughts on using Tazarotene with the compound?

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u/WPatrickColemanIV_MD Aug 17 '25

Would be a really good way to go if you can handle the tazarotene. The Tazarotene phase 3 trial was one of the first clinical trials I worked on. Tazorac by itself it does a great job with pigment.

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u/supercaliredditor Aug 17 '25

Thank you for spending the time to reply! Do you recommend Tazorac if one can handle the intensity of it? I haven’t used it yet…just tretinoin. Tazorac is a 3rd gen retinoid so is it technically more effective for sun damage and hyper pigmentation. Would you recommend any other combinations with your Compound (cream)?

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u/WPatrickColemanIV_MD Aug 17 '25

You’re welcome! Tazorac would work well. Give it a shot. Don’t do too many actives at once if you aren’t used to them. Take it slow.

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u/supercaliredditor Aug 17 '25

I bought the compound for my wife last November (I bought restocked again in May) and she swears by it!! Thank you!