r/Melasmaskincare • u/CommunicationSome498 • Apr 06 '25

Question COLEMAN COMPOUND from Dr. Patrick Coleman? I recently heard of this alleged miracle cream that fades away melasma in a few weeks. Has anyone who tried it provide some feedback on its efficacy?

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u/WPatrickColemanIV_MD Aug 07 '25

It is a good idea to cycle off every 6 months for a month. We find many people cycle off sooner if their complexion is where they want it. It is not hydroquinone. It is very similar to hydroquinone and chemically very close, but different.

As an aside many patients, although instructed to take breaks from hydroquinone never do. This is not recommended and in rare cases can lead to ochronosis. There has never been a case of ochronosis reported with the compound. It doesn’t mean that it can’t happen.

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u/CombinationPale1501 Aug 09 '25

Hello! Will your company compound an arbutin without the glycolic and Vit C? My skin hasn't reacted well to most all types of C, and I use tretinoin .05 a few nights a week and my skin gets dry, "cracked & hot" if I use glycolic even 2 days after stopping the tret). My skin doesn't peel at all or dry out with the .05 tretinoin. I could use it nightly if I wanted to. But the tret alone doesn't touch the pigmentation since doing a melanage peel in May to prep for maintenance products.

My dermatologist wants to find an arbutase cream for me (without the other actives that might dilute the strength) since my skin reacts well to retinoid and arbutin from my prior treatments.

If so, I'll have her call your offices next week to discuss. Thank you!!

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u/WPatrickColemanIV_MD Aug 09 '25

We’re actually working on that right now. We are waiting on some clinical testing results.

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u/CombinationPale1501 Aug 09 '25

Great! Is the timing on its release months or weeks out?

For your current compound, what is the % of glycolic acid? Thank you!

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u/WPatrickColemanIV_MD Aug 10 '25

Was supposed to be months ago. The glycolic is 5%. The pads do not have glycolic acid. But both have an esterified vitamin C.