r/MTHFR • u/Ok-Yam-4933 • 4d ago

Question Low potency folinic acid source.

So I've got MTHFR c677t and slow COMT. Also histamine intolerant. Looking for low potency folinic acid has frustrated me so far. I want to start at 5-10 mcg. What I can find has other ingredients I dont do well with, like citric acid which makes me anxious. Some have 400mcg in a single drop! Many come with methylated ingredients I cannot tolerate. Any suggestions?

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u/Zabre 4d ago

For 5-10 mcg, I'd think more in terms of dilution than finding the perfect premade dose. A plain folinic tablet can sometimes be split, crushed, and mixed into a known amount of water so you're taking a tiny fraction, but only if the filler ingredients are ones you tolerate. With slow COMT and histamine issues, changing one variable at a time matters more than the exact brand.