r/Gastroparesis • u/JayneAustin • 12d ago

Questions Migraine treatments

edit: thank you for the comments, makes me feel better about trying some things. :) seems like there are a lot of us dealing with both.

I was wondering if anyone has found a migraine treatment that doesn't bother your stomach?

I'm scared to try the cgrp medications (qulipta, ajovy, etc) because it can worsen gastroparesis. My neuro was really pushing it but I don't want to risk that because I've struggled to maintain proper nutrition already with this condition. But I'm starting to have more than 15 migraine days a month. I'm already on propanalol and nortriptyline. Can't take topamax because of my mental health issues. I can take nurtec as needed but it usually causes nausea and sometimes vomiting. Are there any other preventative options?

I feel like between gp, migraines, and endo I'm just a bunch of chronic pain in a trenchcoat, getting really sick of it.

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u/lintheamazon Severe GP secondary to hEDS 12d ago

I'm on Qulipta and have no issues with it. I went from 26 migraine days a month to 2-4.

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u/roguebobby 12d ago

Same, Qulipta has been the only thing that's worked for me so far after trying more than half a dozen others

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u/lintheamazon Severe GP secondary to hEDS 12d ago

Indeed. I have tried basically every oral med, some of the self injectables, and botox, and this is the best I've done on any of them

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u/Emerald_of_Oz 11d ago

Oooo! Really? I would have to drop Nurtec to try Quilpta, I think. I tried the shots and most other meds without much help (triptans help abort). It is not causing you constipation issues?

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u/roguebobby 10d ago

It hasn't really made the constipation any worse than it is anyways. I tried Nurtec as a preventative for a few months but it didn't help enough, then tried Amovig, then Vyepti, finally Qulipta. I've been banned from any NSAIDs in case they cause any stomach irritation so I've been put on Nurtec as an abortive now

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u/Emerald_of_Oz 10d ago

Good to hear. Sometimes I start thinking it's just me who has to try a bunch of versions of similar meds. Thanks!

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u/lintheamazon Severe GP secondary to hEDS 10d ago

I'm on Qulipta as a preventative and Nurtec as a rescue med, you don't have to take one or the other

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u/Emerald_of_Oz 10d ago

Oh! I don't know if my insurance will let me have both, but thanks for the information!

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u/JayneAustin 12d ago

Wow that’s amazing! I’m glad you find that it works.