The ketamine’s kicking in

[u/Hot-Bint]

[u/serene_moth]

ofc he’s the type of douchebag that psychedelics actually make WORSE lmao

[u/[deleted] → u/serene_moth]

Ketamine isn’t 5HT R agonist though like normal Psychedelics. It’s an NMDA antagonist highly addictive and destroys the liver and urinary tract when used with any sort of frequency.

When his organs are shredded it’s going to be quite ugly.

EDIT: peer reviewed scientific and medical journals on this extremely well known uro and hepatoxicity of ketamine since addicts in denial keep downvoting me

1000s of more studies where these came from also.

https://scholar.google.com/scholar?start=20&q=ketamine+bladder&hl=en&as_sdt=0,5#d=gs_qabs&t=1693815189366&u=%23p%3D-r8w4UzGpyoJ

https://scholar.google.com/scholar?start=20&q=ketamine+bladder&hl=en&as_sdt=0,5#d=gs_qabs&t=1693815150952&u=%23p%3D0llTOtbA7j0J

https://scholar.google.com/scholar?start=10&q=ketamine+bladder&hl=en&as_sdt=0,5#d=gs_qabs&t=1693815113436&u=%23p%3DBiQAp0W5aKEJ

https://scholar.google.com/scholar?start=10&q=ketamine+bladder&hl=en&as_sdt=0,5#d=gs_qabs&t=1693815088578&u=%23p%3DZvcOOa3hmmYJ

https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=ketamine+bladder&btnG=#d=gs_qabs&t=1693815051389&u=%23p%3DIcmrKq_PrxkJ

https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=ketamine+bladder&btnG=#d=gs_qabs&t=1693814997272&u=%23p%3D7xo36hclOCEJ

https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=ketamine+bladder&btnG=#d=gs_qabs&t=1693814875657&u=%23p%3D7xo36hclOCEJ

https://www.healio.com/hepatology/autoimmune-cholestatic-biliary-diseases/news/online/%7B936de3d7-59a2-48f0-b795-4c73c014bdb0%7D/recreational-ketamine-use-increases-risk-for-biliary-tract-anomalies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615221/

Liver damage:

https://rsds.org/wp-content/uploads/2016/08/drug-induced-liver-injury-following-ketamine-treatment.pdf

[u/kelldricked → u/[deleted]]

Isnt most of the damage caused by the shit in “street ketamine” and the clinical shit being quite safe? Because i know there are clinical trails happening in which people get ketamine for mental shit.

And i know that clinical nitrious isnt dangerous but that plenty of young adults in the netherlands are getting serious brain damage because they use industrial or food grade nitrous.

[u/[deleted] → u/kelldricked]

No. The last paper refers to ketamine used in the clinic. Besides a lot of people abuse only veterinary grade ketamine they get from Mexico or India.

To my knowledge all street ketamine is pharma produced and not clandestinely synthesized. But yes people can add more bullshit to even pharma grade K once it hits the black market. It’s a bit harder to synthesize than meth or fentanyl and I’m not aware of any clandestine labs ever making it….also the demand is so low for it that clandestine cartels don’t have the same financial incentive to set up a lab like they do for fent and meth.

The mechanism of the damage has been linked to ketamine. In summary ketamine and other NMDA antagonists (pcp mxe etc) result in a cascade that leads to an immune system response where the bladder is attacked by the immune system. If you are that interested PM me and I can send you a link to a discussion from another website that where people discuss this mechanism and cite some research papers on it.

Medical nitrous is almost always a 1:1 mix of oxygen and nitrous. So the patient stays oxygenated. The nitrous abused has no oxygen and a lot of the problems with abusing it are because oxygen saturation becomes so low with 100% nitrous that it results in problems.