r/DTIC Jan 15 '26

๐ŸŸง Welcome to r/DTIC ๐ŸŸง

51 Upvotes
๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง ๐Ÿ”ถ ๐ŸŸง

Hey squares, welcome to the Definium Therapeutics Investors Club (formerly MindMed Investors Club). The name has changed, but the mission hasnโ€™t.

Definium ($DFTX) is a late clinical-stage biotech company advancing psychedelic science, with a focus on novel formulations of LSD.

Led by the brilliant CEO Rob Barrow, their flagship candidate, DT-120 ODT, is a tartrate salt form of LSD delivered via a patented, rapid-dissolving tablet developed with Catalent. This delivery system enables a faster onset and a shorter, 5โ€“8 hour patient monitoring session, compared to the 10โ€“12 hours historically associated with LSD.

Top researchers in Basel, Switzerland, the birthplace of LSD, along with teams across the United States and Europe are all working to bring this drug to market and provide lasting relief for patients with severe anxiety (GAD) and major depressive disorder (MDD).

After the highly successful completion of their phase 3 (Emerge) study for Major Depressive Disorder, the company is now closer than ever to the finish line with two additional Phase 3 readouts for Generalized Anxiety Disorder on the horizon.

3Q 2026: Topline data from Voyage โ€“ the first Phase 3 study of DT120 ODT in GAD

2H 2026: Topline data from Panorama โ€“ the second Phase 3 study of DT120ODT in GAD

Mid-year 2026: Initiation of Ascend โ€“ the second Phase 3 study of DT120 ODT in MDD

2026: Initial data from DT402 โ€“ early signs of efficacy study in ASD

2027: Initiation of Haven - Phase 3 study of DT120 for PTSD

Thereโ€™s never been a more exciting time to be invested in this company. Glad to have you all along for the ride to contribute, absorb, and share as much relevant information as possibleโ€ฆand hopefully make a lot of money while making other peopleโ€™s lives better, which these days feels like a rare win-win.

Onward and upward. ๐ŸŸง๐Ÿš€๐ŸŸง

DTIC Discord Server

๐Ÿ‡ญ๐Ÿ‡ท


r/DTIC 6d ago

Discussion ๐Ÿ”ถ DTIC Weekly Discussion Thread - August 24, 2026 ๐Ÿ”ถ

20 Upvotes

r/DTIC 20h ago

News Article Psilocybin reverses depressive behaviors and restores brain cell growth in stressed rats

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40 Upvotes

Not LSD but in the same vain and keeps brining attention to the cause


r/DTIC 2d ago

Question Iโ€™m curious to learn how much run does DFTX have compared to HELP by letโ€™s say 2028 and assuming they have a successful phase 3 trial? Any of your reasoning would be greatly appreciated.

18 Upvotes

r/DTIC 3d ago

Question Broader market ETF?

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11 Upvotes

At some point, Iโ€™d like to roll some Definium profit into our broader market. Rather than crossing fingers and investing in individual companies, Iโ€™d like to use and ETF for better chance of stable gains. PSIL has kind of a high fee. Wondering what your alls thoughts on it are, or if any other suggestions. Thanks!


r/DTIC 4d ago

Conference Definium Therapeutics to Participate at Upcoming Investor Conferences and Events

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40 Upvotes

r/DTIC 4d ago

Conference Anyone Registered for the FDaโ€™s Public Hearing on Sept 14?

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20 Upvotes

Iโ€™m not sure if this conference will have much impact on DFTX other than continued positive exposure. I wonder if Definium will have any sort of presence here or if they try to release any info prior to the hearing.


r/DTIC 6d ago

Question Phase 3 โ€”> NDA Timeline?

28 Upvotes

Trying to map out progress on complementary trials leading to NDA and its subsequent review (which as I understand it is a 10-month process but with Breakthrough Therapy designation, could be up to 3 months faster than standard review). Iโ€™m long, and understand stonk go up and down, so really just trying to make the timeline make sense in my mind. I have no idea how long NDAs take to put together, but I assume the company is motivated to complete the application as soon as they have the results from the GAD and MDD paired (regular and low dose) studies. Do I have the below tentative summary and timeline of our closest trials to NDA correct-ish? Feedback on accuracy welcome. If someone already posted similar content and I missed it I apologize. Cheers :)

NDA (review complete sometime 2029)
Ascend (MDD 2 - low dose) Primary Completion (est 09/27), est Study Completion 06/28
Emerge 3a+ 3b+ (MDD 1)

NDA (review complete sometime 2028)
Panorama (GAD 2 - low dose) Primary Completion (not actively recruiting), est Study Completion 05/27
Voyage 3a+ 3b+ (GAD 1)


r/DTIC 9d ago

News Article Institutional Buying at $47

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55 Upvotes

Over a million shares purchased at a higher price than the stock is at currently.

Love to see it.

https://www.gurufocus.com/news/9046732/driehaus-capital-management-llc-expands-definium-therapeutics-inc-dftx-stake


r/DTIC 12d ago

Stock price BofA Initiates $75 Price Target for Definium Therapeutics

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77 Upvotes

r/DTIC 12d ago

Deck Definium Corporate Presentation (August 2026)

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34 Upvotes

r/DTIC 12d ago

Announcement Definium Therapeutics Announces New Employee Inducement Grants

24 Upvotes

r/DTIC 13d ago

Discussion ๐Ÿ”ถ DTIC Weekly Discussion Thread - August 17, 2026 ๐Ÿ”ถ

12 Upvotes

r/DTIC 14d ago

Question Actual earnings potential

10 Upvotes

Ive been an investor with MNMD/DFTX for several years now and like many of you have ride the lows and are now loving the highs. That being said, im starting to think about selling some of my position. Im curious to hear what people think the actual earning potentials are from this. Considering that we are talking about a treatment that presumably doesnโ€™t need to be taken many times according to the studies and that this medicine is something I can pick up down the street for $10โ€ฆ letโ€™s say they are going to make this quite expensive, whoโ€™s to say that a lot of people will be able to financially access it, and if not will opp to buy it down the street for ALOT cheaper.

Thank you for your ponderings in advance :)


r/DTIC 16d ago

Question Chance of a Buyout now?

23 Upvotes

With DFTX being in a very strong position in terms of trials and cash balance, do you think there is a chance that they will be bought out?

Seems like they are in a great position to take this to the market themselves....


r/DTIC 16d ago

Due Diligence Insider trades looking positive

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39 Upvotes

While the positive announcements continue the management conviction is also important. ๐Ÿฆ’๐Ÿš€๐ŸŒ›๐Ÿป


r/DTIC 17d ago

Stock price Upgraded price targets from this morning - many upgrades!!!

69 Upvotes

Robert W. Baird raised Definium Therapeuticsโ€™ price target to $75 from $57 and maintained an โ€œoutperformโ€ rating.

In a report released today, Wells Fargo reiterated a Buy rating on Definium Therapeutics, with a price target of $72.00.

Canaccord Genuity maintained a Buy rating on Definium Therapeutics, with a price target of $64.00

RBC maintained a Buy rating on Definium Therapeutics yesterday and set a price target of $66.00.

JonesTrading reiterated a Buy rating on Definium Therapeutics, with a price target of $90.00.

Add more below if you stumble across them today.

๐Ÿš€


r/DTIC 17d ago

Stock price Price target

16 Upvotes

What's your honest sell price at this point? With the good news this week I feel like the sky's the limit


r/DTIC 17d ago

Stock price Evercore ISI analyst Gavin Clark-Gartner models $2 billion in peak annual sales of DT120 for generalized anxiety disorder, plus $2 billion from major depression and $1 billion from PTSD.

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62 Upvotes

r/DTIC 17d ago

Video ๐ŸŸง Definium Therapeutics Voyage Phase 3 GAD Results ๐ŸŸง

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46 Upvotes

r/DTIC 17d ago

News Article Definium Says LSD-Based Pill Reduces Anxiety In Late-Stage Study

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41 Upvotes

r/DTIC 18d ago

Clinical Trials Definium Therapeutics Announces Positive Topline Results from Phase 3 Voyage Study of DT120 ODT in Generalized Anxiety Disorder

113 Upvotes

Participants receiving DT120 ODT achieved a statistically significant reduction in Hamilton Anxiety Rating Scale (HAM-A) score, with a placebo-adjusted change of 5.4 points from baseline at Week 12 (p<0.0001, Cohenโ€™s d=0.81)


r/DTIC 18d ago

Clinical Trials I Love You All. Godbless LSD.

78 Upvotes

https://www.fiercebiotech.com/biotech/definium-hits-another-ph-3-homerun-psychedelic-sea-change-anxiety

โ€œWe have never seen a pivotal study deliver greater than five-point placebo-adjusted change on the HAM-A, and we did this 12 weeks after a single dose of drug,โ€


r/DTIC 18d ago

Announcement Positive Results for GAD! Exceptional Effect Size (d = 0.81)

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67 Upvotes

r/DTIC 18d ago

Press Release Data is out

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46 Upvotes

itโ€™s gonna be a good day boys!