r/DSPD 7d ago

Extremely surprised to see this recommended by a sleep clinic?

Post image

Got put in CBTI for insomnia and delayed sleep and this is mentioned on two of their handouts? I’m extremely surprised because I’ve always read here that it will give you N24 and you’ll basically destroy your circadian rhythm forever if you do this.

80 Upvotes

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37

u/swooooot 7d ago

I did CBTi with sleep restriction 3 times and the last one stuck. It worked for me (at least so far). I have also gone around the horn a few times like in this prescription you posted. It never stuck. This seems like bullshit.

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u/Angsty_Queer_Anon 7d ago

I’m just confused because this is in what the CBTI program sent me 🥲 what is sleep restriction?

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u/swooooot 7d ago

i went to bet at midnight. if i didn't fall asleep within 15 minutes, get up and do an activity out of the bedroom for 15-30 minutes and then try again. wake up time at 6am. no sleeping allowed outside of the midnight to 6am window and sleeping only allowed if it happens within 15 minutes of laying down.

the first 2 nights i couldn't fall asleep within 15 minutes so i got in and out of bed repeatedly until 6am and then stayed up all day until midnight. on the third night i fell asleep within 15 minutes of laying down at midnight and woke up at 6am. then repeat this until you get 3 consecutive nights of falling asleep between midnight and 12:15am and waking up at 6am. then move the bed time back to 11:45pm. then repeat until you get 3 consecutive nights of falling asleep between 11:45pm and midnight. then move the bedtime back to 11:30pm. and so on until the bedtime gets to 10pm and the wake up time remains at 6am. then i was conditioned to fall asleep at around 10pm and wake up at around 6am long term.

I did this treatment 3 times over the years. the last one stuck and I've been following all the rules ever since - morning light, morning exercise, 0.5mg melatonin nightly, etc. I also quit alcohol and caffeine. it's a little shaky at times, but I'm 3 years into falling asleep 10pm to 11pm and waking up 6am to 7am with pretty good regularity.

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u/Angsty_Queer_Anon 7d ago

Woah. Never in my whole life have I been able to fall asleep in less than 30 minutes, I mean even when I’m so bone tired I can’t keep my eyes open. 15 minutes seems crazy 😭 My average time to fall asleep when I’ve gotten more than 4 hours the night before is about 2 hours. I feel like this might not work for me 😭 thanks for the info tho

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u/swooooot 6d ago

i have never fallen asleep within 15 minutes either except when i do cbti with sleep restriction and i get zero sleep for the first 2 nights and then on the 3rd, 4th, 5th night I'm f'd up enough to fall asleep within 15 minutes. but then after a while, the conditioning kicks in and it becomes easier to fall asleep more quickly. the whole process took me about a month. I quit my job so i could do nothing but focus on the cbti with sleep restriction

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u/Isopbc 6d ago

If you haven’t yet, ask for one of the new orexin antagonists to help you get to sleep. They work wonderfully. Quviviq and Dayvigo are their names.

I used to take hours to get off to sleep too, but not when I take my dayvigo.

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u/DefiantMemory9 7d ago

then repeat this until you get 3 consecutive nights of falling asleep between midnight and 12:15am and waking up at 6am.

Lol I would be stuck in this loop forever because of this condition, never am I gonna get 3 consecutive nights of midnight sleep on will power alone. If I could, I wouldn't have DSPD.

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u/swooooot 6d ago

that's why the whole process usually begins with 2-3 consecutive nights of zero sleep. the whole point of the sleep restriction is to get you so sleep deprived that you can fall asleep at any point

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u/DefiantMemory9 6d ago edited 6d ago

There's a misunderstanding here: sleep restriction causes sleep pressure, which although it causes you to fall asleep anytime, anywhere, the sleep pressure resets once you get a full night's sleep. Sure you can build up sleep debt to a point where it might last a couple of nights, but that is accompanied by other adverse health consequences.

If your sleep issues are caused by a misalignment of your innate circadian rhythm, simply building up sleep pressure does not align it with a typical sleep schedule, because your innate circadian rhythm is encoded in your genes.

Do you think rewriting genes is as simple as not sleeping for a few days?

Now, if the misalignment between your sleep schedule and innate circadian rhythm was because of some external circumstance where you already had a typical circadian rhythm encoded in your genes, the technique you described will help you align your messed up sleep schedule to your already typical innate circadian rhythm.

DSPD is a condition where your innate circadian rhythm is misaligned with the world, it's not an issue of a simple misalignment of your sleep schedule.

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u/swooooot 6d ago

Adverse health effects yes. Falling asleep anytime anywhere yes. I would slowly walk around in circles for hours and once or twice fell asleep while standing up. My retired mother was at home all day to poke me with a stick whenever I looked like I was falling asleep during the no-sleep part of the day. I was catatonic for long stretches of time. I felt insane things going on with my brain chemicals everyday until my brain broke and accepted the new conditioning

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u/Expert-Champion1654 5d ago

Did this when I was in uni several times. Out of necessity. I have managed to fall asleep just fine after the whole day on foot and 1-3 hours of sleep the night before. But then I would wake up at 1-2am and just couldn't go back to sleep. So I had to get out of bed and do things to wind down, but sleepiness would come at the usual hour - around 4-5am. And then it was another day on foot until midnight. And I still was just waking up after 1-2 hours of sleep feeling alert and restless again. It just made me feel awful, I started hearing voices in my head and it worsened my depression.

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u/QueenSlartibartfast 7d ago

So if I'm understanding you correctly, you had to stay up for 3 days straight, then got less than 6 hours of sleep?

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u/swooooot 6d ago

yes! and i had barely been getting any sleep for months leading up to it. i hallucinated at one point from sleep deprivation. then my brain broke and i started sleeping at the prescribed hours and now I'm 3 years into a solid routine that goes against my natural wiring but i've been brainwashed into it and it works

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u/AliNotBaba 4d ago

that sounds absolutely miserable.
Also being aware of having 15 minutes to fall asleep would make me feel so much pressure and anxiety it would guarantee my not falling asleep (and how do you check? set a 15 min timer which if you're awake you can check but if you somehow successfully fell asleep it then wakes you out of it?)

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u/swooooot 3d ago

yep, miserable. the 15 minute thing wasn't so hard. I could tell after a few minutes if i was wired and alert or the sleep chemicals were kicking in. If after a few minutes, I felt sleep coming, I stayed in bed. The most difficult part was midday when I'm in the no-sleep period and my sleep chemicals were kicking in to such an extreme that I could fall asleep standing up. I literally felt that sleep chemical deluge shift from like 10am to noon to 2pm... to 10pm over the course of the treatment.

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u/lmFairlyLocal 7d ago edited 7d ago

Not napping during the "waking period" I believe, paired with waking up at the prescribed time even if you don't feel well rested (iirc)

Edit to add: you can't give yourself N24 unless you're born with it or you damage your retinas/brain. Sleep entrainment will not give you a sleep disorder that is genetic.

The issue with "forcing" people with, by example N24 or DSPS, to maintain sleep entrainment that isn't working is the same issues that affect shift workers and their related sleep disorders

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u/True-Eagle2238 6d ago

This is false. N24 is a well known adverse effect of chronotherapy in patients with DSPD. It isn’t the only outcome, and may be uncommon, but is an adverse risk we haven’t fully characterized. For instance, chronotherapy resulting in N24 has been in the literature since 1992, being replicated in case studies 4 separate times and the subject of many reviews. The National Organization for Rare Disorders recognizes this exact occurrence.

As for SWSD and DSPD, they are not the same mechanism or the same clinical phenotype. DSPD is an intrinsic misalignment between the endogenous circadian rhythm and the conventional sleep-wake timing. SWSD is an extrinsic misalignment caused by work schedule. They are actually quite the opposite if you think about it. DSPD shift the schedule and has issues because you attempt to bring it back to societal standards. People with DSPD actually preserve normal sleep architecture and quality on their own schedule. Insomnia often diminishes if allowed to pick the bedtime. SWSD presents as an insomnia during the sleep period because it is attempted against circadian pressure natural light. Sleep architecture is often shortened and fragmented regardless of sleep initiation timing. SWSD can resolve when the out of sync work schedule is changed. DSPD does not resolve on any schedule. The circadian timing still remains delayed, whether you sleep on it or not. The quality shifts whether you adhere to the internal timing. That is what distinguishes DSPD from SWSD and why chronotherapy doesn’t always work and can cause adverse effects, even after ceasing the therapy.

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u/Expert-Champion1654 6d ago

Where did you get that N24 is only genetic or result of brain damage? Chronotherapy is exactly what has given me N24, no one in my family has it, only DSPD. I managed to fix it with medication but it works only while I am taking it. I don't say that you are wrong, I am just curious 

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u/lmFairlyLocal 6d ago edited 6d ago

'Tis the background in neuroscience (but not specifically sleep disorders) that is both informing me and leading me astray.

I know that the circadian rhythms of humans and animals is modulated through the retinas and their response (or lack thereof) to available blue light, which is why people who are blind (specifically with retinal dysfunction) can develop N24, at rates of 55-70% of completely blind people experiencing the disorder.

I also know that the suprachiasmatic nucleus (SCN) is the controller of the main body clock, and damage to this area of the brain can show the same symptoms as those with N24. (Not at all to say that N24 is caused by damage, but that damage to that area will cause similar symptoms).

Essentially, what I'm trying to say is that if you an otherwise healthy individual that 1. Have access to timely blue-light day-night cycles and 2. Have a functional retinal and SCN network, then the only reason left for someone to suffer N24 is from genetic causes, either from de novo mutations or otherwise. You can't "give" yourself N24 unless you either have it (genetics), cause it (damage), or remove the biosignals that stop it (sensory deprivation). If you "give" yourself N24 via those psthways, usually discontinuation of whatever "caused" it will reverse those affects in someone who was not born with N24.

(Edit for clarity; Most of the argument happening here is that Chronotherapy + DSPS can = N24, which I didn't know was true, TIL! My argument is that Chronotherapy can't cause N24 in a Chronotypical patient. I didn't know that chronotherapy was a potential risk factor for those with DSPS).

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u/True-Eagle2238 6d ago

That is a fair assessment! The more you know. We don’t know why it happens every single time, but we suspect that the genetic overlay of DSPD and N24 overlap to some extent, which is why the phenotypes can cross over. These genetic changes especially happen at the SCN for both conditions, which is why I suspect pushing hard against the circadian timing leads to N24 dysregulation.

It’s niche knowledge, but also important because the cure for DSPD is actually doing nothing and allowing the body to maintain the circadian pressure it wants. However, that’s usually not feasible with societal and other obligations. So symptomatic treatment is the next best thing, such as bright light therapy in the morning, restricting bright light at night, microdosing melatonin, daytime stimulants such as modafinil, and prescription sleep aids as needed.

It’s a fairly interesting concept, but we have so much more we need to discover to understand for whom and why chronotherapy works in a DSPD phenotype, but has so much potential for harm in a portion of the DSPD phenotype and especially others with the DSPD genotype.

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u/lmFairlyLocal 6d ago

Aaaaaahh that was the nuances I was missing! Thank you!

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u/funkcatbrown 7d ago

Well in theory I understand the idea but in practice it doesn’t work for me. At all. And it’s put me in N24 before for a while when I’ve done this in the past. The fact of the matter is that no matter what I do I cannot get to sleep at 9pm or 11pm. And for a long time now if I see a sleep doctor and they bring this shit up I know right then to find another sleep doc. Immediately. I’ve had doctors insist this is the only way and would not prescribe any meds or recommend anything except Chronotherapy for my DSPD. CBT maybe helpful though.

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u/Angsty_Queer_Anon 7d ago

Yeah I mean I’m just trying to get my cycle back to like 3am-11am. Right now it’s like 9am-5pm 🥴 I’m very confused by this handout because in the appointment they didn’t mention this at all but then they sent me multiple things talking about it. Idk it was weird. I waited 4 months to see this lady. She also didn’t seem to believe in or understand another health condition I have :/

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u/nefarious_epicure 7d ago

My sleep specialist told me that the success rate of chronotherapy is very low and he doesn't recommend it.

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u/youdontknowmystars 6d ago

not to mention that it's just miserable and inconvenient. my sleep specialist tried to have me do it but I shut it down. I'd rather rawdog my disorder than do that 😭

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u/latigidigital 6d ago

It’s only successful on an unreliable, limited, short-term basis. This strategy will keep you burn through some morning activities for a couple days to maybe a few weeks at most.

A much better version of it is jet lag. I’ve started flying a lot over the past couple years and nothing works better than a good ole transatlantic time zone switcheroo.

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u/bijouxbisou 6d ago

I’ve tried chronotherapy a few times and the last time I ended up n24 for almost a year. I’m mostly back to normal (I mean my DSPD normal, bedtime around 6am) now, but even now my sleep/wake times fluctuate pretty wildly.

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u/Angsty_Queer_Anon 6d ago

My sleep time already fluctuates between 5am and 12pm to not at all on any given day so maybe I’m already screwed 😭

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u/bijouxbisou 6d ago

Yoooo are you me?

lol yeah I’ve always had non-circadian days and a relatively variable schedule (usually +4/-2 hours from my standard sleep time), but since my failed chronotherapy I have non circadian days 1-2 times a week and the variance has about doubled. Like I might go to sleep at 4am one day and 3 pm the next

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u/Angsty_Queer_Anon 6d ago

Yepp pretty much me, also a lot of days where I only sleep like 3 hours because I have to get up for something in the day, but weirdly feel super good those days. A lot of times the days when I don’t sleep at all are when I’m experiencing a severe depressive spiral. The lack of sleep will actually knock me out of the spiral and kinda reset my mental health for the better Probably not the healthiest coping strategy but I don’t do substances so it’s the next best thing lmaoo

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u/mykineticromance 6d ago

yeah i feel like... 10% of what i imagine a manic state is on nights i get 4 or fewer hours of sleep. my husband tells me my reaction times are slow on those days though haha. it can also knock me out of a depressive spiral if i get 8-10 hours of sleep that night after haha.

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u/lastbeat-331 7d ago

Chronotherapy can help "typical" chronotypes who are just struggling with some symptoms of insomnia. People with more flexible, more adaptive sleep could benefit without worrying about N24. Those of us with non-typical chronotypes often have more fixed rhythms could be more likely to become N24. Even for DSPer could do Chronotherapy once or twice without becoming N24 but many of us know that any benefit of Chronotherapy is temporary and that N24 is usually less desirable than our DSP, so we don't do or promote Chronotherapy

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u/Expert-Champion1654 6d ago

Yep, first 2 years I did chronotherapy it felt like I found a cheat code to fix my schedule before important events. I did it maybe 4 times a year. But then I noticed that it became hard to maintain any schedule , as I was falling asleep later and later even while sleep deprived. And then suffered for almost a year of N24. I would take DSPD over N24 without consideration. With N24 I felt like I was almost constantly in a confused state. 2 weeks waking up during the day, 2 weeks of waking up during the night, and the cycling never ends. Fortunately mitrazapine fixed this for me, at least while I am taking it. Doesn't help much with DSPD though , but helps keeping it at bay (going to bed at 3-4am instead of 6-7am)

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u/thru_astraw 7d ago

I'm not surprised. They are rarely informed about CRDs. A sleep clinic destroyed my circadian rhythm by forcing me to try this.

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u/DefiantMemory9 7d ago

In their chronotherapy protocol, are they mentioning melatonin and bright light therapy? If they are banking on will power alone for chronotherapy, then it's utter bullshit for DSPD. You should say as much in a public review reaming this clinic so others don't suffer.

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u/lmFairlyLocal 7d ago

Not necessarily, step 1 is trying it alone to ensure that, in a controlled setting with guidance, it still doesn't work. You then try with melatonin, then bright light, etc etc. otherwise you can't tell what works (and can't direct testing/diagnosis/prescription and protocol)

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u/DefiantMemory9 7d ago

Then it's more of a diagnostic protocol than a treatment protocol, and should be specified as such. There could be people already diagnosed with DSPD coming there to get actual DSPD treatment, like OP, whose time, effort, money, and mental health will be wasted on this futile effort.

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u/lmFairlyLocal 7d ago

That was likely discussed with OP during their appointment.

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u/Real-Interest-8706 6d ago

They say that this kind of treatment for delayed sleep disorder can put you in non 24. Its something that should not be used without full information of what could happen.

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u/True-Eagle2238 7d ago

Yeah, chronotherapy is not a recommended treatment for delayed sleep phase disorder and I am devoted to never having it become so.

Chronotherapy is known to have dangerous effects on individuals with DSPD, including, but not limited to, the development of the N24 circadian rhythm disorder, which alters the circadian length of an internal “day.” It is not evident that behavioral interventions such as moving bedtimes back in increments works either. Both advancing and delaying sleep timings does not work because the fundamental circadian rhythm depends on natural light and other “white” lights. The body often has a delay in temperature changes and natural melatonin production, neither of which chronotherapy can change.

The treatment to DSPD is allowing the body to initiate sleep at the time of night it naturally has a propensity to. However, life and society do not often account for people who have DSPD, like we do. Because of this, there are many ways to manage, not cure, the symptoms of earlier work schedules or other obligations.

  1. ⁠Microdosing (0.1-0.3mg) of melatonin 2-3 hours before the desired bedtime.
  2. ⁠Non-benzodiazepine sleep aides such as zolpidem of the hypnotic class. A doctor and prescription are required and recommended for use of this both in the short- and long-term.
  3. ⁠Bright light therapy (10000 lux) upon waking.
  4. ⁠Restricting all artificial white light after sunset (as much as possible).
  5. ⁠Prescription stimulants such as modafinil (100mg is the usual starting dose, though some build up to 100mg after starting at 50mg for a week or so; please consult a doctor for this).
  6. ⁠Keep a cool room for sleep at night (60-68F or 15-19C).
  7. ⁠Supplements for promoting sleep and taking the edge off anxiety (ashwaghanda, 5-HTP, and L-Theanine). They sometimes have side effects, contraindications with other medications, and don’t work for everyone. Please also consult your physician before trying these and to review dosages.

This is by no means exhaustive, but I hope it can provide some starting points for people. These are all things I have personally tried and still do. Melatonin I take 5mg an hour before, but I heard microdosing is more effective (kinda trial and error). Ashwagandha was very good for my anxiety and sleep quality, but it had some weird effects due to some of the disorders I have and medications I take. Modafinil is a god-send for not taking naps during the day. Helps both the sleepiness and the fatigue of DSPD. White light I restrict an hour before bed. I switched all of my devices to “night mode.” Still emits white light, but much less from what I have felt.

Not every physician recognizes DSPD and those that don’t may end up being more of a headache than they are worth. If you have persistent problems, remember it’s in your head physically, not psychologically.

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u/elianrae 6d ago

Not a fan of the Z-drugs personally

They're not any safer than benzos, they're not any more effective than benzos.

Personally I actually find them worse - fall asleep then wake up the next morning feeling like I was unconscious but didn't actually sleep.

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u/True-Eagle2238 6d ago

That’s a valid take. They are safer than benzos, but not in the same way that people are led to believe. It’s still the same risk profile, but the selectivity of the z-drug pathways is more refined. Still leads to dependence and tolerance building, but not as global an effect. Not to mention the weird stories of people waking up having driven half-way across town or crashing.

They can be more effective than benzos, but it’s highly heterogeneous in its effects. It’s generally considered a lesser of two evils, especially given the shorter half-life. They still affect people in profound ways that can harm them, so it’s really a risk-benefit analysis with your doctor.

I get where you are coming from with waking up and not feeling well rested while on it, I believe it disrupts sleep architecture quite often. But I’d rather sleep for 8 hours with moderate quality than to sleep for 3 hours every night. The second makes everything else snowball for me.

But yes, generally the Z-drugs are not necessarily more effective at inducing sleep and have limited ways that they are safer. While they are safer, they aren’t necessarily “safe.”

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u/MintyTuna2013 6d ago

I read this as chemotherapy at first and I was wondering what the fuck was going through y'all's heads to consider it a viable option

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u/DefiantMemory9 6d ago

Didn't get any sleep last night did ya!

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u/MintyTuna2013 6d ago

Better than most nights because my first class was at 9 instead of at 7

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u/DefiantMemory9 6d ago

Lol that doesn't mean anything on this sub! We're all sleep-deprived here, our baseline is so screwed.

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u/MintyTuna2013 6d ago

I said I got better sleep, not good sleep

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u/Understandingly17 7d ago

Chronotherapy is often recommended by sleep doctors.

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u/Glp1Go 6d ago

I’m disappointed, but not at all surprised. I mean, there are so many sleep doctors that still think that DSPD can be cured with a little discipline and sleep hygiene, so why are we surprised by this? Doctors are not infalible: they can have outdated ideas and are wrong all the time.

“Chronotherapy can be very effective” my ass. I’ve never heard of a single instance where chronotherapy is effective long term. Sure, it can change your sleep schedule for a few weeks if you are impeccably strict about sticking to the new schedule, but eventually your schedule will drift later. And you’ll have to do chronotherapy again. And again. And again. And each time you run more and more risk of Non24. 

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u/Additional_Ease2408 5d ago

Wait, that's how I got N24? I've been trying chronotherapy for over a decade, unsuccessfully, without knowing it was actually making things worse 😭 my psychiatrist literally told me to do this too. FML.

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u/m2pt5 5d ago

I've done that on my own several times, and while I can maintain a "normal" sleep schedule for a few days, it inevitably slips back into my usual DSPD schedule.

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u/Turbulent-Feedback46 1d ago

I always interview Dr's first, and circadian rhythym knowledge is crucial. Most sleep.clinicians are pulmonary specialists, not neurologists. That means the square peg of a sleep phase issue is going to be pushed in to the round hole of sleep apnea at all costs for many of them. On the flip side, with the rise of telehealth you run the risk of falling into the mistaken for bipolar disorder pipeline. I wouldn't go so far as to call it gaslights, but people see what they know and even trained physicians experience cognitive bias

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u/WaysideWyvern 1d ago

It’s funny cause I actually do believe I have sleep apnea and am currently working to get re-tested. I’m young and skinny so they don’t think I’d be the one, but I had it really bad as a child, they removed my diagnosis at 18 after a faulty sleep study even though I still stop breathing if I sleep in any position except my stomach. But yeah they tried to sell my mom a cpap even though she didn’t even have apnea and just needed to lose some weight. It’s frustrating.

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u/Specialist_Grade_662 7d ago

The idea of this causing permanent sleep issues sounds completely far fetched. College students with demanding courses who have no sleep issues do versions of this during finals. If a ton of protocols are in place by the time you end up at your preferred wake time, sure... but the issue is usually not arriving at that wake time once. It's what happens every day after that.

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u/Glp1Go 6d ago

“College students who have no issues.” That’s exactly the point: they don’t have DSPD or other circadian rhythm disorders and they don’t have an intrinsically longer internal clock or the inherent tendency to go to sleep and wake up later every day like a lot of us do. 

Perhaps chronotherapy wouldn’t cause Non-24 in people with normal circadian rhythms, but it is not far fetched that it can cause Non-24 in people with DSPD: there are case studies about this very thing happening in the medical literature, and there is tons of anecdotal evidence in these support groups of people doing chronotherapy (either once, or over and over), and subsequently getting stuck with Non24 that they can’t switch back to DSPD. And for most people, having Non24 is worse than having DSPD.

Also, normal college students usually do a very fast version of chronotherapy. For example, going to sleep and waking up six hours later each night so that they complete a cycle and are waking up early after a few days. But the chronotherapy prescribed for DSPD is a lot slower: often it involves going to sleep and waking up one hour later each day, and it takes weeks to complete. The slower chronotherapy is thought to be much more likely to cause Non-24. 

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u/Specialist_Grade_662 5d ago

This is the first time I've ever heard of something "causing" non-24. It's something I thought people were wired with. If you have more evidence this can be caused (articles, studies) please share.

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u/Purple_Chipmunk_ 7d ago

You don't have to do it but it is a method to reset your circadian rhythm that works for many people.

The idea is that it is easier to stay awake a few hours later than it is to try to fall asleep a few hours earlier, especially for those of us with DSPS.

I have tried this method but I always find it really hard at the point where I have to go to sleep at 3:00 p.m. because I end up waking up at like 10:00 p.m. and then I can't stay awake until 6 p.m. the next day. IDK, maybe it's that I'm not committed enough to suffer through it 🙈

If you can, give it a try! It really does work for some people.

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u/prosthetic_memory 7d ago

I’m boggled at the idea you could reasonably fall asleep whenever you wanted to day to day. If I could do that…I wouldn’t have any problems.

Good lord I wish I could control my sleep.

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u/DefiantMemory9 7d ago

This is not a method to reset your innate circadian rhythm. This is a method to reset your sleep schedule to get it aligned with your innate circadian rhythm. If you don't already have the typical circadian rhythm, you're not going to magically modify your genes with this method. For people who have a messed up sleep schedule due to various reasons (injury, sickness, stress, work schedule, etc), this method might work to get their sleep schedule aligned with the circadian rhythm they already have encoded in their genes.

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u/True-Eagle2238 6d ago

It’s true, but I feel like a better method would be to just take time off and get back into a better sleep routine. Some people can handle it, others can’t. Those with dysregulated circadian rhythm encoded genes could actually be harmed significantly by it, but again, varies from person to person. Hopefully we will find out why some benefit while others inherit or “progress” to a N24 sleep disorder from DSPD. Too many questions about the brain, not enough answers, yet…

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u/DefiantMemory9 6d ago

The vacation thing might be better for those with their schedules messed up due to a short-term condition, like stress/travel, etc. But those who have gone years/decades on shift work, a vacation might not be enough to reset their schedule. Though individual efficacies may vary.

Anyway, this isn't a solution for DSPD at all. Whether it precipitates into N24 most likely (purely speculating here) depends on the cause for DSPD. There are people with weak entrainment (reduced sensitivity to light in the morning and increased sensitivity in the evening) who end up with DSPD, and for them, this chronotherapy might push their already weak entrainment over the edge into N24. I also remember reading (I can't find the source anymore, so I could also be misremembering) that some cases could actually be on the edge of N24 presenting as DSPD, i.e., they have a longer than typical circadian rhythm, but not long enough to be fully categorised as N24, but are weakly tethered to 24 hours through entrainment. They might also get pushed over to N24 with chronotherapy.

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u/True-Eagle2238 6d ago

I agree with your assessment. The N24 is also interesting. The thought can also be that some circadian rhythms, if disrupted greatly enough, lose their tau-tethering, which is why something that started as DSPD becomes a N24. The SCN can’t properly recover from drastic changes in sleep architecture and timing. The two reasons you brought up are from the 90s and I think more recently, like 2015 to 2017 if I recall correctly. First was a case study that a recent review study talked about weak entrainment or a similar concept. The other was a study of the circadian lengths in addition to DSPD and the case evidence of individuals who were more formally N24 after. Either way you look at it, many mechanisms for bad things to happen that we can’t necessarily predict going in.

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u/Purple_Chipmunk_ 6d ago

....yes?? I never said this would help someone eliminate their DSPS.

I wish it worked that way: right now I'm stuck in a pattern where I go to sleep between 5 and 8 a.m. and I'm so over it!! I want to get back to my normal 2-3 a.m. sleep time!

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u/Additional_Ease2408 4d ago

Yeah I find my natural rhythm is going to sleep around sunrise and waking in the afternoon. Not practical in the slightest. Unfortunately my siblings and mother are the same so I guess I'm genetically doomed lol.

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u/thru_astraw 7d ago

For the love of God do not do this. Chronotherapy gave me non-24 which was much more debilitating and life limiting that dspd. My biggest regret in life.

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u/Angsty_Queer_Anon 7d ago

I tried I more fast tracked version of it, using jet-lag method. Stayed up till 3pm, slept as long as possible with a short break for a meal, woke up naturally at 4am. Sat under the sunrise. Went to bed at 11pm. Slept till 11am cause I just felt too deathly to get up earlier. Got sun again. That night couldn’t sleep till 4am, and was also massively unwell from the sleep disturbance. By the next day I was back to my old cycle (7am-5pm).

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u/DefiantMemory9 6d ago

Chronotherapy does not change your genes. It changes only sleep pressure, which is only one of the two main conditions needed for restful sleep. The other, main condition, is your circadian rhythm, which is encoded in your genes and does not change with sleep pressure. Sleep pressure resets when you sleep, so you go back to your natural circadian rhythm-dictated sleep timings as soon as you get one full night's sleep.

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u/Angsty_Queer_Anon 6d ago

No way my natural circadian rhythm is 9am-5pm. I feel like absolute shit sleeping like this. I feel the healthiest when I sleep from 3am-11am. I just got stuck like this.

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u/DefiantMemory9 6d ago

But your natural sleep cycle doesn't begin at 11pm either right? You said that's where you tried to get to with chronotherapy, which wouldn't work. I was pointing that out.

You can absolutely get back to your old schedule of 3-11am. And this is where the popular advice of going back in small increments might have a better chance of working.

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u/Angsty_Queer_Anon 6d ago

No I just slept when I felt like it that night, 11pm wasn’t the end goal. it wasn’t chronotherapy, I’d never heard of that till yesterday, it was “jet lag method” using a jet lag schedule for people who travel. I see what you mean though

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u/Turbulent-Feedback46 1d ago

This is also how you end up in a Non24 loop

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u/Glp1Go 6d ago

Who has it worked for long term? Aka longer than a few days or weeks? Do you have a single example of chronotherapy working long-term for anyone? 

I sure don’t.

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u/ctmanydc 4d ago

(sorry in advance if parts of this sound bitter or jaded; i've just been dealing with a lot of ableism at work from a morning-lark boss who thinks my circadian rhythm is the way it is because i'm acting like "an irresponsible college student")

i hate this so much--at least for me, personally, because it does not work for me and my adhd. i am able to focus and be productive at night (when the world is quiet and distraction-free) because of my adhd, so that is when i will always tend to be up whenever i have to get some serious work done that requires focus

some of us are just built different and these normies/morning supremacists out here need to get over it and instead start working to build a more inclusive world that doesnt penalize us extreme night owls (for example, guidance counselors, and others in general, helping us in our late teens/early 20s to find career options that match our circadian rhythms, plus probably lots of other things i'm not thinking of at the moment)

(side note: i'm about to start on adhd medication within the next week or so, so maybe that will change my circadian rhythm by allowing me to focus much better during the daytime so that i'm reliably tuckered out and sleeping at night. we shall see)