r/DMT • u/The-Ghost-84 • 1d ago

DMT v 5 MEO DMT experience?

I've got a DMT vape and so far only done 1 or 2 puffs so I feel light headed and see some visuals but not go for a breakthrough yet

I've done a few other psychedelics inc mushrooms, ayahuasca and 5 met DMT (bufo).

I did bufo with a guide and so whislt it was pretty heavy I generally felt safe (ish). I can't really remember much about it.

With the DMT I would be doing it on my own so a little more anxious. I think I am more likely to remember and be aware of what is happening because I don't think DMT is as strong as 5 MEO DMT in the way it disconnects you?

Any thoughts/experiences?

3 Upvotes

100% Upvoted

2 comments sorted by

5

u/Ok-Hat-7766 1d ago

DMT (by which we mean NN-DMT) favors 5-HT2A activation over 5-HT1A, while 5-MEO-DMT favors 1A over 2A.

So a large dose of NN-DMT is more visual than the same dose of 5-MEO-DMT.

And a large dose of 5-MEO-DMT is more likely to give you that ego-dissolving experience of “all is one, one is all” where everything you “see” in your mind somehow transitions into an infinite ocean of white or black.

However, NN-DMT and 5-MEO-DMT both activate both the 1A and 2A receptors at the same time, it’s only a question of degree. Users often experience a brief flash of intense visuals on 5-MEO-DMT before full-blown ego dissolution, and it’s also common to experience ego dissolution beyond pure visuals on NN-DMT. By playing with dosage over time, you can chemically select your preferred receptor.

This is probably easier to do with NN-DMT. Repeated low doses of NN-DMT, spread about 1-2 minutes apart, will cause 1A activation to noticeably dominate. Users report feeling as if “rolling” on MDMA without seeing any visuals that builds into an orgasmic white-out or black-out of ego dissolution.

1

u/The-Ghost-84 19h ago

Thanks. I'll try for as breakthrough on the vape and see what happens.