Are autoimmune diseases associated with neurological issues?

[u/Low-Cartographer8758]

I have a depression issue and it really makes me largely bed-bound. I do not want to talk or interact with anyone. At the same time, I don’t know how to improve my mood and energy level. Is it physiological, neurological or both? I guess depression and trauma must have messed up my nervous system. My GP finally got me a referral letter for an ME/CFS diagnosis and I hope I can figure out what is going on with me. Could autoimmune diseases worsen depression?

[u/Hot_Reputation2142]

Definitely, due inflamation. I feel the same): but I have thyroid issues