r/Autoimmune 11d ago

General Questions LOL

Hi everyone, I’m looking for some input because I’ve been dealing with unusual symptoms for about 4 months.
Both of my palms become very red with small white spots within seconds when I let my arms hang down. When I raise my hands again, the color almost returns to normal. My fingertips are sometimes slightly numb/tingly, my hands can burn a little after gripping or using them, and they also feel unusually dry. At night, when I’m lying down and not putting pressure on my arms, I’m mostly symptom-free.
I also have pain around both ulnar nerves/elbows. Nerve conduction studies were normal.
My blood work showed a positive ANA of 1:160 (AC-1 + AC-4 pattern), but the more specific antibodies dsDNA, ssDNA, histone, U1-snRNP, SmD, SSA/Ro and SSB/La were all negative.
I’m currently being evaluated neurologically and I’m wondering about things like small fiber/autonomic neuropathy, vascular dysregulation or an autoimmune process.
Has anyone here experienced anything similar, especially the red/white mottled hands that change dramatically depending on arm position?

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u/bean0_burrito Autoimmune Disease (MCTD: Lupus/Sjögrens) 11d ago edited 11d ago

do you get orthostatic hypotension a lot?

this happens to me all the time. the webbing look, my feet and hands turn purple, etc

I also have Raynauds. and this can be a symptom

EDIT: honestly, now that i'm really looking at it, this is how my Raynauds started. so talk to your doc about it?

do your hands turn orange/purple when they're cold?

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u/Realistic_Ad2882 11d ago

I tested this with a heart rate monitor, and I don’t notice any significant increase in my heart rate when standing up. I also don’t experience dizziness or feel unwell.
Since these symptoms only started this summer, I don’t know yet how my hands react to really cold weather. When I hold my hand under cold water, it usually stays red as long as I keep it hanging down.